Enhanced rehabilitation program for patients recovering from major trauma

Pragmatic Prospective, Multicentre Feasibility Non-randomised Controlled Trial on Enhanced Rehabilitation for Poly & Lower Extremity Trauma (PROPERLY Trial)

Not applicable Interventional Manchester University NHS Foundation Trust · NCT05652790

This study is testing a new rehabilitation program for people recovering from major trauma to see if it helps them recover better compared to standard care.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment50 (estimated)
Ages18 Years and up
SexAll
SponsorManchester University NHS Foundation Trust Government
Locations1 site (Manchester, Greater Manchester)
Trial IDNCT05652790 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility of recruiting patients who have survived major trauma for an enhanced rehabilitation service. Participants will be offered the Enhanced Rehabilitation Programme (ERP), which includes two sessions per week lasting 60-120 minutes, and will undergo various functional assessments and patient-reported outcome measures at different intervals. Additionally, a Standard Care (SC) group will be included for comparison, providing data on usual therapy outcomes. The study will identify barriers to recruitment and service delivery, as well as appropriate outcome measures for future larger trials.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 years old with polytrauma or severe isolated injuries, residing in Greater Manchester, and willing to engage in the enhanced rehabilitation program.

Not a fit: Patients under 18 years old or those unable to participate in the rehabilitation program due to health or logistical reasons may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved rehabilitation strategies for patients recovering from major trauma.

How similar studies have performed: While similar rehabilitation approaches have been explored, this specific enhanced program is novel in its focus on major trauma recovery.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Participants over 18 years old
* Registered GP in Greater Manchester or Greater Manchester Resident.
* Polytrauma or one or more complex /severe isolated injury
* Rehabilitation goals (e.g., mobility, function, job retention/ return to work) identified using shared decision-making process
* Patient able to enter programme 6-30 months post injury.
* For the ERP patients willing to travel to the MIHP for their evaluation and treatment twice a week.
* Participants with lower limb injuries that continue to have functional impairment.
* Participants deemed well and safe enough to participate by clinical teams.
* Normal ECG if previously reported to have abnormal ECG
* Participants willing to consent to follow up over 12 months
* Participants with the capacity to consent to the study.
* Fully healed wounds and bone healed sufficiently to allow at least partial weight bearing

Exclusion Criteria:

* Participants under the age of 18
* Participants unable to provide informed consent
* Participants with multiple pre-existing comorbidities that affect ability to participate in enhanced rehabilitation such as cognitive impairment, unstable angina.
* Central motor neurological impairment affecting ability to participate in an enhanced rehab programme
* Absence of functional disability affecting gait and / or function.
* Plans for further surgery that will impact on gait or function.

Where this trial is running

Manchester, Greater Manchester

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Major Trauma
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.