Enhanced recovery (ERAS) after minimally invasive stomach cancer surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, randomized, open-label, multicenter trial compares a structured ERAS protocol with conventional perioperative care in adults undergoing elective laparoscopic or robotic gastrectomy for gastric cancer. Patients were randomized 1:1 (154 per group) to receive either the ERAS pathway or usual care, with ERAS elements including preoperative carbohydrate loading, shorter perioperative fasting, and multimodal opioid-sparing analgesia. The primary outcome is the proportion of patients who meet standardized discharge criteria at 9:00 AM on postoperative day 4, and secondary outcomes include EQ-5D-5L quality-of-life scores, pain at rest and with coughing, I-FEED gastrointestinal function, postoperative nausea and vomiting, major complications (Clavien-Dindo), and length of hospital stay. The open-label design and multiple high-volume centers aim to generate results that reflect real-world implementation of ERAS in minimally invasive gastrectomy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adults aged ≥19 years scheduled to undergo elective laparoscopic or robotic gastrectomy for gastric cancer
* American Society of Anesthesiologists physical status classification I to III
* Ability to provide written informed consent, demonstrate understanding of the study protocol, and complete patient-reported outcome measures appropriately

Exclusion Criteria:

* Requirement for resection of organs other than the stomach during surgery (except for cholecystectomy)
* History of upper abdominal surgery (except for cholecystectomy)
* Known hypersensitivity to fentanyl, ropivacaine, acetaminophen, or non-steroidal anti-inflammatory drugs
* Determined by the investigator or study personnel to be otherwise unsuitable for participation in the study

Where it's running

• Dongsan Hospital, Keimyung University School of Medicine
  Daegu, South Korea Recruiting
• Seoul National University Hospital
  Seoul, South Korea Recruiting
• Pusan National University Hospital
  Busan, South Korea Not yet recruiting
• Chungnam National University Hospital
  Daejeon, South Korea Not yet recruiting
• National Cancer Center
  Goyang, South Korea Not yet recruiting
• Seoul National University Bundang Hospital
  Seongnam, South Korea Not yet recruiting

Study contacts

• Principal investigator: Do Joong Park, MD, PhD — Seoul National University Hospital
• Study coordinator: Hojin Lee, MD, PhD
• Email: hjpainfree@snu.ac.kr
• Phone: 82-2-2072-2467

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.