Enhanced physical exercise program for cognitive health in older adults
Physical Activity Component of the Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER): Study Protocol and Feasibility of the Assessment
This study is testing if a personalized exercise program can help older adults with early signs of memory problems improve their thinking skills and overall well-being.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of Patras Academic / other |
| Locations | 2 sites (Pátrai, Achaia and 1 other locations) |
| Trial ID | NCT06528379 on ClinicalTrials.gov |
What this trial studies
The Greek Interventional Geriatric Study to Prevent Cognitive Impairment and Disability (GINGER) focuses on individuals with Subjective Cognitive Impairment (SCI) and includes a six-month physical activity intervention. This component aims to assess whether a tailored physical exercise program can lead to improvements in cognitive function, physical abilities, quality of life, and overall wellbeing. The study is conducted across multiple centers, coordinated by the University of Patras, and involves comprehensive cognitive assessments to ensure participants meet eligibility criteria. Participants will engage in individualized exercise regimens designed to enhance their cognitive and physical health.
Who should consider this trial
Good fit: Ideal candidates for this study are older adults with subjective cognitive decline but without objective cognitive impairment.
Not a fit: Patients with mild cognitive impairment, dementia, or significant psychiatric or neurological disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this intervention could significantly improve cognitive function and quality of life for older adults experiencing subjective cognitive decline.
How similar studies have performed: Other studies have shown promising results with physical activity interventions in cognitive health, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria include people with: * Subjective Cognitive Decline confirmed from the Subjctive Cognitive Decline Questionnaire (SCD - Q score \>7) * Absence of objective cognitive imparement as confirmed from cognitive assessment tests (i.e. MoCA, Trail A \& B, Stroop, RCFT, FAS. ) Exclusion Criteri include people with: * Mild Cognitive Impairement (MCI) or dementia * Chronic psychiatric or neurological disorders affecting cognition (i.e. bipolar disorder, schizophrenia, MS, TBI, Parkinson's disease etc.) * Unstable pathological diseases (i.e. uncontrolled hypothyrodism, athythmias, uncontrolled hypertension, high blood pressure at rest etc.) * Recent (\<6 month) surgery, which restrics active participation in exercise/physical activity * inadequate knowledge of Greek
Where this trial is running
Pátrai, Achaia and 1 other locations
- Laboratory of Clinical Physiotherapy and Research, Department of Physiotherapy, University of Patras — Pátrai, Achaia, Greece (Recruiting)
- Department of Psychiatry, School of Medicine, University of Patras — Pátrai, Greece (Recruiting)
Study contacts
- Study coordinator: Evdokia Billis, PhD
- Email: billis@upatras.gr
- Phone: 00306973047170
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.