Enhanced daily disinfection to reduce contamination in hospital rooms
Determining the Impact of Enhanced Daily Disinfection on Environmental Contamination in Acute Care Hospital Rooms: A 3-arm Multicenter Blinded Randomized Controlled Trial
NA · Duke University · NCT05739955
This study is testing if a new type of disinfectant can better clean hospital rooms and reduce germs compared to regular cleaning methods.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 918 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Duke University (other) |
| Locations | 1 site (Durham, North Carolina) |
| Trial ID | NCT05739955 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of enhanced daily disinfection strategies in reducing environmental contamination in acute care hospital rooms. It compares two intervention methods: a standard EPA-registered disinfectant and a quaternary ammonium, salt-based germicidal wipe with 24-hour activity. Each hospital room will be randomly assigned to one of the interventions or a control group receiving routine disinfection. The goal is to determine if these enhanced methods significantly lower the bioburden compared to standard practices.
Who should consider this trial
Good fit: Ideal candidates include adult patients admitted to hospital rooms for at least 48 hours and on contact precautions.
Not a fit: Patients expected to stay less than 48 hours or those on respiratory precautions due to specific viral infections may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved infection control practices in hospitals, enhancing patient safety.
How similar studies have performed: Other studies have shown success with enhanced disinfection methods, indicating potential for meaningful improvements in hospital infection control.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient admitted to the room * Patient spent ≥1 night in room prior to enrollment * Anticipated patient stay of ≥48 hours * On contact precautions (for any reason) and/or has positive culture for EIP at the time of room admission Exclusion Criteria: * Patient stay is expect to be \<48 hours * Patient age \<18, even if on adult ward * Patient admitted on respiratory precautions due to coronavirus disease (COVID-19), influenza, or respiratory syncytial virus (RSV) * Patient on contact precautions due to C. difficile
Where this trial is running
Durham, North Carolina
- Duke University — Durham, North Carolina, United States (RECRUITING)
Study contacts
- Principal investigator: Deverick Anderson, MD — Duke University
- Study coordinator: Amanda M Graves, MPH
- Email: amanda.m.graves@duke.edu
- Phone: 919-681-7957
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Disinfection, Contamination