Engaging patients in healthy opioid prescriptions through community pharmacies

Healthy Opioid Prescription Engagement 2.0

Not applicable Interventional University of Utah · NCT05141266

This study is testing if a new program led by pharmacists can help adults who misuse opioids get better support and reduce their misuse compared to regular medication advice.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment350 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Utah Academic / other
Locations1 site (Salt Lake City, Utah)
Trial IDNCT05141266 on ClinicalTrials.gov

What this trial studies

This study is a randomized controlled trial conducted across 14 community pharmacies to evaluate the effectiveness of the Brief Intervention-Medication Therapy Management (BI-MTM) intervention in reducing opioid medication misuse. The trial will compare the pharmacist-led BI-MTM approach to standard medication counseling among adults who have screened positive for opioid misuse. Participants will be assessed at baseline, 2 months, and 6 months to measure changes in opioid misuse behaviors, with data linked to state prescription drug monitoring for objective outcomes. The study aims to leverage community pharmacies as a resource in addressing the opioid epidemic.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who speak English and have screened positive for opioid misuse.

Not a fit: Patients who are pregnant or those who cannot provide reliable contact information or access to their prescription monitoring data may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly reduce opioid misuse and improve patient health outcomes in the community.

How similar studies have performed: Other studies have shown promise in utilizing community pharmacies for opioid misuse interventions, indicating a potential for success with this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult (≥18 years)
* English speaking
* Not receiving cancer treatment
* Who have a positive opioid misuse screen on the POMI will be eligible to learn about this study

Exclusion Criteria:

* Are pregnant (given potential pre/post-natal opioid use complications among pregnant women/offspring
* Can-not provide collateral contact information for ≥2 contact persons (to ensure consistent contact/follow up)
* Do not have a reliable land line or mobile phone to be contacted by study staff
* Are filling only buprenorphine (given some formulations are not indicated for pain)
* Plan to leave the area for an extended period of time in the next 6 months
* Have had a psychotic and/or manic episode in the last 30 days (before consent, patients will be asked to screen for psychosis
* Do not provide permission to access their state prescription drug monitoring data.

Where this trial is running

Salt Lake City, Utah

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid MisuseOpioid-Related DisordersPharmacist-Patient RelationsCommunity PharmaciesPatient NavigationOpioid intervention
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.