Endotracheal suctioning during positive-pressure extubation in the ICU

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized, controlled trial comparing endotracheal suctioning versus no suctioning during positive-pressure extubation in mechanically ventilated adults. Eligible patients intubated for more than 48 hours and cleared for extubation by their physician are randomized at the time of planned extubation. Respiratory rate, pulse oximetry, and inspired oxygen fraction are recorded for three hours after extubation to calculate the ROX index as the primary short-term outcome. Vital status is recorded up to 28 days after extubation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Adult patient
* Intubated for more than 48 hours
* Patient for whom extubation is prescribed by the patient's physician

Exclusion Criteria:

* Headboard restriction\>30°.
* Decision to limit active treatment in advance of reintubation
* Protected person (under guardianship or curatorship)
* Person under court protection
* Persons deprived of liberty
* Persons not affiliated to a social security scheme
* Pregnant or breast-feeding woman
* No co-inclusion with a study whose period of interest is follow-up within 3 hours of extubation.

Where it's running

• Centre Hospitalier Universitaire d'Orléans
  Orléans, Loiret, France Recruiting

Study contacts

• Principal investigator: Cécile FOSSAT — Centre Hospitalier Universitaire d'Orléans
• Study coordinator: Cécile FOSSAT
• Email: fanny.louat@chu-orleans.fr
• Phone: +33238575252

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Evaluating Heart Function During Breathing Trials in ICU Patients

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.