Clinical trial Recruiting at 1 site Interventional Ages 18 to 100

Endoscopic ultrasound-guided liver biopsy using a dynamic wet technique

Official title: Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique

Run by Sohag University · NCT06833619 · Data updated 2026-11-12

This study is testing a new way to do liver biopsies using ultrasound to see if it makes the procedure safer and more accurate for patients with different health conditions.

Quick facts

Study typeInterventional
Ages18 Years to 100 Years
SexAll
Enrollment30 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag)
StatusRecruiting
StartedDecember 1, 2024
Main results expectedJanuary 1, 2026
Study endsJanuary 1, 2027
Registry record updatedFebruary 19, 2025
Trial IDNCT06833619 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults requiring a liver biopsy due to altered liver function tests.

Probably not a fit

Patients on anti-platelet or anticoagulant therapy, those with moderate-to-gross ascites, or severe liver disease (Child C cirrhosis) may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) using a dynamic wet technique, which aims to improve the safety and accuracy of liver biopsies. The procedure allows for real-time visualization of the needle entering the liver, minimizing the risk of injury to intrahepatic vessels and bile ducts. It is particularly beneficial for patients with altered liver function tests and can be performed safely in individuals with higher international normalized ratios (INR) compared to traditional methods. The study focuses on assessing the outcomes of this technique in various patient populations, including those who are obese or pregnant.

Why it matters

Potential benefit: If successful, this technique could provide a safer and more effective method for obtaining liver biopsies, leading to better diagnostic outcomes for patients.

How similar studies have gone: While EUS-LB has shown promise in previous studies, its widespread use is still limited, indicating that this approach is not yet fully established in clinical practice.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* The participants of the study were adults in need of liver biopsy for the evaluation of Altered liver function test

Exclusion Criteria:

* Using anti-platelets or anticoagulants within the last 5days
* Inability to provide informed consent
* Moderate-to-gross ascites
* Child C cirrhosis
* INR more than 2.01
* Platelet count less than 50,000/µL3

Where it's running

  • Sohag University
    Sohag, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Browse more
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.