Endoscopic ultrasound-guided liver biopsy using a dynamic wet technique
Efficacy of Endoscopic Ultrasound Guided Liver Biopsy Using Dynamic Wet Technique
This study is testing a new way to do liver biopsies using ultrasound to see if it makes the procedure safer and more accurate for patients with different health conditions.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Sponsor | Sohag University Academic / other |
| Locations | 1 site (Sohag) |
| Trial ID | NCT06833619 on ClinicalTrials.gov |
What this trial studies
This study evaluates the efficacy of endoscopic ultrasound-guided liver biopsy (EUS-LB) using a dynamic wet technique, which aims to improve the safety and accuracy of liver biopsies. The procedure allows for real-time visualization of the needle entering the liver, minimizing the risk of injury to intrahepatic vessels and bile ducts. It is particularly beneficial for patients with altered liver function tests and can be performed safely in individuals with higher international normalized ratios (INR) compared to traditional methods. The study focuses on assessing the outcomes of this technique in various patient populations, including those who are obese or pregnant.
Who should consider this trial
Good fit: Ideal candidates for this study are adults requiring a liver biopsy due to altered liver function tests.
Not a fit: Patients on anti-platelet or anticoagulant therapy, those with moderate-to-gross ascites, or severe liver disease (Child C cirrhosis) may not benefit from this study.
Why it matters
Potential benefit: If successful, this technique could provide a safer and more effective method for obtaining liver biopsies, leading to better diagnostic outcomes for patients.
How similar studies have performed: While EUS-LB has shown promise in previous studies, its widespread use is still limited, indicating that this approach is not yet fully established in clinical practice.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The participants of the study were adults in need of liver biopsy for the evaluation of Altered liver function test Exclusion Criteria: * Using anti-platelets or anticoagulants within the last 5days * Inability to provide informed consent * Moderate-to-gross ascites * Child C cirrhosis * INR more than 2.01 * Platelet count less than 50,000/µL3
Where this trial is running
Sohag
- Sohag University — Sohag, Egypt (Recruiting)
Study contacts
- Study coordinator: Sara Elbadry Elrabie, master
- Email: elbadrysara615@gmail.com
- Phone: 01023941334
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.