Endoscopic treatment for Zenker's diverticulum
Official title: Clinical Outcome of Endoscopic Treatment for Zenker's Diverticulum
Run by Istituto Clinico Humanitas · NCT03948438 · Data updated 2026-11-12
This study is testing new, less invasive methods to treat Zenker's diverticulum and see if they can help reduce symptoms for people with this condition.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Istituto Clinico Humanitas Academic / other |
| Locations | 1 site (Rozzano) |
| Status | Recruiting |
| Started | January 1, 2009 |
| Main results expected | December 30, 2028 |
| Study ends | December 30, 2028 |
| Registry record updated | September 21, 2022 |
| Trial ID | NCT03948438 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients experiencing symptoms of Zenker's diverticulum who are seeking endoscopic treatment.
✕Probably not a fit
Patients who are pregnant or breastfeeding will not benefit from this study due to exclusion criteria.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the safety and effectiveness of endoscopic techniques, such as flexible endoscopic septum division (FESD) and per-oral endoscopic septotomy (POES), for treating Zenker's diverticulum, a rare condition characterized by an outpouching at the pharyngoesophageal junction. By using minimally invasive methods, the study aims to provide an alternative to traditional surgical approaches. The research will measure the severity of symptoms in patients undergoing these endoscopic procedures.
Why it matters
Potential benefit: If successful, this study could offer a safer and less invasive treatment option for patients suffering from Zenker's diverticulum.
How similar studies have gone: Other studies have shown promising results with similar endoscopic approaches for treating Zenker's diverticulum, indicating potential for success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients with symptomatic ZD treated by endoscopic procedures Exclusion Criteria: * pregnancy and breastfeeding
Where it's running
-
Humanitas Research Hospital
Rozzano, Italy Recruiting
Study contacts
- Study coordinator: Alessandro Repici, Prof.
- Email: alessandro.repici@hunimed.eu
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Evaluating the use of endoscopic myotomy for gastrointestinal motility disorders
This study is testing how well a procedure called endoscopic myotomy works for people with different gastrointestinal motility disorders like achalasia and gastroparesis over several years.
-
Registry for advanced endoscopic procedures
This study is collecting information from patients who are having advanced endoscopy procedures for gastrointestinal diseases to see how well these treatments work and improve patient care.
-
Comparing treatments for Zenker Diverticulum and related swallowing issues
This study is testing which treatment method works better for people with Zenker's diverticulum and swallowing problems by comparing surgery through the neck to a less invasive endoscopic approach.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.