Endoscopic techniques for closing esophageal wall defects
Outcomes of Endoscopic Management of Esophageal Wall Defects at a Large Referral Center
This study is testing different ways to close holes in the esophagus to see which method helps patients heal better after surgery or other issues.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Sex | All |
| Sponsor | Indiana University Academic / other |
| Locations | 1 site (Indianapolis, Indiana) |
| Trial ID | NCT04571541 on ClinicalTrials.gov |
What this trial studies
This study compares the outcomes of various endoscopic closure techniques, such as stenting and suturing, for treating esophageal wall defects, which can arise from surgical procedures or spontaneously. These defects pose significant health risks, and timely intervention is crucial for patient recovery. The research is conducted at Indiana University, a leading center for complex thoracic surgery and esophageal disease, utilizing innovative endoscopic methods to improve healing outcomes. The study aims to establish the effectiveness of these techniques in reducing morbidity and mortality associated with esophageal defects.
Who should consider this trial
Good fit: Ideal candidates include any patients with spontaneous or iatrogenic esophageal wall defects.
Not a fit: Patients without esophageal wall defects or those who do not require intervention for their condition may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a less invasive treatment option for patients with esophageal wall defects, potentially improving healing rates and reducing complications.
How similar studies have performed: Other studies have shown promising results with endoscopic techniques for similar conditions, indicating a growing body of evidence supporting this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Any patient with spontaneous or iatrogenic esophageal wall defect Exclusion Criteria: * None
Where this trial is running
Indianapolis, Indiana
- Indiana University Hospital — Indianapolis, Indiana, United States (Recruiting)
Study contacts
- Study coordinator: Martha Mendez
- Email: mwmendez@iu.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.