Endoscopic cutting and abdominal extraction device versus conventional scalpel for removing large uterine tissue during laparoscopic hysterectomy

Comparison of Endoscopic Tissue Cutting and Abdominal Extraction Device With Conventional Cold Scalpel

Not applicable Interventional Ege University · NCT07226375

This trial will test whether a new endoscopic cutting and extraction device can remove large uterine tissue faster and with fewer complications than the usual scalpel for people having laparoscopic hysterectomy with an estimated uterine weight of 500 g or more.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment84 (estimated)
Ages35 Years to 65 Years
SexFemale
SponsorEge University Academic / other
Locations1 site (Izmir)
Trial IDNCT07226375 on ClinicalTrials.gov

What this trial studies

The trial compares vaginal tissue morcellation using a novel endoscopic cutting and abdominal extraction device to conventional scalpel morcellation in people undergoing planned laparoscopic hysterectomy. Participants meet inclusion criteria including an estimated uterine weight of at least 500 grams and will undergo tissue extraction with one of the two techniques during their operation. Key outcomes include successful tissue removal, extraction time, need to enlarge incisions or convert to open surgery, and surgical complications. The device is a patented design developed with TUBITAK support and the procedure is being performed at an Izmir surgical site affiliated with Ege University.

Who should consider this trial

Good fit: People scheduled for laparoscopic hysterectomy with an estimated uterine weight of 500 g or more who are sexually active and can have their operation at the Izmir site are the intended participants.

Not a fit: People with smaller uteri (under 500 g), those who are sexually inactive, or those unable to travel to Izmir are unlikely to be eligible or benefit from this trial.

Why it matters

Potential benefit: If successful, the device could speed up tissue removal, reduce the need to enlarge incisions or convert to open surgery, and shorten recovery time.

How similar studies have performed: Conventional scalpel morcellation and power morcellators are established but have limitations and risks, while this specific endoscopic extraction device is novel and has limited prior clinical outcome data.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Planned laparoscopic hysterectomy
* Estimated uterine weight of 500 g or more

Exclusion Criteria:

* Sexual inactivity

Where this trial is running

Izmir

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Laparoscopic Hysterectomylaparoscopic hysterectomymorcellationtissue extraction
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.