Clinical trial Recruiting at 3 sites Interventional Ages 50 and up

Embolization treatment for knee osteoarthritis

Official title: A Prospective, Single-arm, Multinational, Multi-center, Clinical Study to Evaluate the Performance and Safety of Musculoskeletal Embolization Using NBGM200 in Patients With Knee Degenerative Osteoarthritis

Run by Next Biomedical Co., Ltd. · NCT06930677 · Data updated 2026-11-12

This study is testing a new treatment called embolization therapy to see if it can help people with knee osteoarthritis feel less pain and move better.

Quick facts

Study typeInterventional
Ages50 Years and up
SexAll
Enrollment72 (estimated)
SponsorNext Biomedical Co., Ltd.
Industry-sponsored
Locations3 sites (Ghent and 2 other locations)
StatusRecruiting
StartedApril 17, 2025
Main results expectedFebruary 2027
Study endsFebruary 2027
Registry record updatedNovember 19, 2025
Trial IDNCT06930677 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are individuals diagnosed with knee osteoarthritis confirmed by MR-imaging.

Probably not a fit

Patients with current local infections or a life expectancy of less than six months may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of embolization therapy using NBGM200 in patients diagnosed with knee osteoarthritis. The approach involves targeting the affected area to potentially alleviate pain and improve function. Patients will be selected based on MR-imaging confirmation of osteoarthritis, while those with local infections or limited life expectancy will be excluded. The study aims to evaluate the safety and efficacy of this novel treatment method.

Why it matters

Potential benefit: If successful, this treatment could provide significant pain relief and improved mobility for patients suffering from knee osteoarthritis.

How similar studies have gone: While embolization therapy is a novel approach for knee osteoarthritis, similar studies in other conditions have shown promising results, suggesting potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Osteoarthritis proven by MR-imaging

Exclusion Criteria:

* Current local infection
* Life expectancy less than 6 months

Where it's running

  • University Hospital Ghent
    Ghent, Belgium
    Recruiting
  • Uz Leuven
    Leuven, Belgium
    Recruiting
  • Elisabeth-Tweesteden Hospital
    Tilburg, Netherlands
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.