Electroacupuncture for chronic urinary retention due to lower motor neuron lesions

Effects of Electroacupuncture of Different Treatment Frequency in Chronic Urinary Retention Caused by Lower Motor Neuron Lesions: a Prospective Cohort Study

This study is testing how different frequencies of electroacupuncture can help people with chronic urinary retention caused by lower motor neuron lesions feel better.

Quick facts

• Study type: Observational
• Enrollment: 100 (estimated)
• Ages: 18 Years to 80 Years
• Sex: All
• Sponsor: Guang'anmen Hospital of China Academy of Chinese Medical Sciences (other)
• Locations: 1 site (Beijing)
• Trial ID: NCT06354244 on ClinicalTrials.gov

What this trial studies

This study aims to compare the effects of electroacupuncture administered at different frequencies (2, 3, and 4 sessions per week) on patients suffering from chronic urinary retention caused by lower motor neuron lesions. Participants will be evaluated based on their post-void residuals and bladder sensation, with the goal of determining the most effective treatment frequency. The study is observational and will involve patients who have been using various methods of catheterization for their urinary retention. The outcomes will help to understand the efficacy of electroacupuncture in this specific patient population.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older diagnosed with urinary retention due to lower motor neuron lesions and who have been experiencing this condition for at least one month.

Not a fit: Patients with lower urinary tract obstructions or severe systemic disorders, as well as those with certain implanted medical devices, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive treatment option for patients with chronic urinary retention, improving their quality of life.

How similar studies have performed: While there is limited data on the specific frequency of electroacupuncture for this condition, similar studies have shown promising results in using electroacupuncture for various urinary disorders.

Eligibility criteria

Inclusion Criteria:

* Diagnosed with urinary retention caused by lower motor neuron lesions (e.g., sacral plexus, cauda equina, or sacral cord lesions).
* 18 years or older.
* Baseline post void residuals (PVR) ≥150 mL.
* The course of urinary retention ≥1 month.
* Having normal bladder sensation.
* Using clean intermittent catheterization (CIC), indwelling catheterization (IC), manual assisted voiding including putting pressure on abdomen, or cystostomy catheterization.
* Signed informed consent and voluntary participation in the study.

Exclusion Criteria:

* Having a lower urinary tract obstruction, such as bladder neck contracture, urethral stricture, prostatic hyperplasia, or large urinary stones that can cause obstruction.
* Having any type of malignant tumors not removed.
* Having severe systemic disorders not controlled.
* Having implanted electrodes of cardiac pacemaker, pudendal nerve stimulation, bladder stimulation, or SNM.
* Pregnancy or lactation.
* Eletroacupuncture treatment duration \< 2 weeks.

Where this trial is running

Beijing

• Guang'anmen Hospital, China Academy of Chinese Medical Sciences — Beijing, China (RECRUITING)

Study contacts

• Study coordinator: Zhishun Liu

Conditions: Urinary Retention, Lower Motor Neurone Lesion, electroacupuncture, chronic urinary retention, cohort study