Effects of whole-body vibration training on muscle flexibility and fatigue after lower extremity burns

Impact of Whole-body Vibration Training on Muscle Flexibility and Fatigue After Lower Extremity Thermal Burn Injury

Early Phase 1 Interventional Cairo University · NCT06787716

This study is testing if whole-body vibration training can help people with serious burn injuries in their legs feel less tired and improve their muscle flexibility during recovery.

Quick facts

PhaseEarly Phase 1
Study typeInterventional
Enrollment80 (estimated)
Ages20 Years to 50 Years
SexAll
SponsorCairo University Academic / other
Locations1 site (Cairo, Giza)
Trial IDNCT06787716 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of whole-body vibration training on improving muscle flexibility and reducing fatigue in patients who have suffered lower extremity thermal burn injuries. Participants will undergo a traditional physical therapy program alongside whole-body vibration therapy, aiming to enhance recovery and overall physical fitness. The study focuses on individuals with significant burn injuries, specifically targeting those with deep second-degree burns covering 35%-40% of their total body surface area. Assessments will be conducted to ensure eligibility based on specific inclusion and exclusion criteria.

Who should consider this trial

Good fit: Ideal candidates are individuals aged 20 to 50 who have sustained a deep second-degree thermal burn of the lower extremity.

Not a fit: Patients with open wounds, recent fractures, severe obesity, cardiorespiratory disorders, or a history of bone disease or traumatic spine issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve muscle flexibility and reduce fatigue in burn patients, enhancing their recovery and quality of life.

How similar studies have performed: While the specific combination of whole-body vibration training and burn recovery is novel, similar approaches in rehabilitation have shown promise in improving physical outcomes in other patient populations.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

1. Patients with a deep second-degree thermal burn of the lower extremity, 35%-40% total body surface area (TBSA) of burn as measured with the rule of nine, after six weeks from the injury or complete wound healing.
2. Patients with 20 to 50 years old.
3. Absence of any neurological disorder i.e.: stroke, ataxia, or parkinsonism.

Exclusion criteria:

1. Patients with open wounds.
2. Patients with recent fractures.
3. Patients with severe obesity BMI ≥40.
4. Patients with cardiorespiratory disorders.
5. Patients with bone disease, joint replacement, and traumatic spine history since last year.

In order to apply the inclusion and exclusion criteria, all cases will be subjected to an interview and assessment.

Those subjects who will be eligible to take part in the study will sign an informed consent before participation in the study.

Where this trial is running

Cairo, Giza

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Lower Extremity Burnsburnflexibilitymuscle fatigueEMG
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.