Effects of Vitamin K2 on Muscle Weakness in Type 2 Diabetes
Effects Vitamin K2 on Muscle Mass and Function in People With Muscle Weakness and Type 2 Diabetes
This study is testing if taking vitamin K2 can help adults with type 2 diabetes who have muscle weakness feel stronger and improve their physical performance.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 150 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Dasman Diabetes Institute Academic / other |
| Locations | 1 site (Kuwait City) |
| Trial ID | NCT05375630 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of vitamin K2 supplementation on muscle size and function in adults suffering from muscle weakness associated with type 2 diabetes. Participants will receive either vitamin K2 or a placebo to assess changes in muscle strength and overall physical performance. The study aims to provide insights into whether vitamin K2 can improve muscle health in this population. It targets adults aged 40 and older who have been diagnosed with type 2 diabetes and exhibit specific criteria for muscle weakness.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40 and older with physician-confirmed type 2 diabetes and muscle weakness.
Not a fit: Patients with a BMI of 45 or higher, those on anticoagulant therapy, or individuals currently taking vitamin K2 supplements may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new dietary recommendations or treatments to enhance muscle function in individuals with type 2 diabetes.
How similar studies have performed: While there is limited data on vitamin K2's effects on muscle weakness in diabetes, similar studies exploring vitamin supplementation for muscle health have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Physician confirmed type 2 diabetes. * Age \>/= 40 years * No changes in anti-diabetic medication in the last 3 months. * Muscle weakness (grip strength \<27kg and females \<16kg) Exclusion Criteria: * BMI of 45 or higher * BP of 160/100mmHg or higher * Cancer or cancer that has been in remission \<5 years * Any medical condition that prevents participants from exercising safely * On anticoagulant therapy * Currently consuming vitamin K2 supplements * Current smoker
Where this trial is running
Kuwait City
- Dasman Diabetes Institute — Kuwait City, Kuwait (Recruiting)
Study contacts
- Principal investigator: Ebaa AlOzairi — Dasman Diabetes Institute
- Study coordinator: Stuart Gray
- Email: stuart.gray@glasgow.ac.uk
- Phone: 01413302569
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.