Effects of Vilanterol and Fluticasone on Exercise Performance

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates how exercise performance in physically active individuals is affected by the acute inhalation of the beta2-agonist vilanterol combined with fluticasone furoate. Participants will receive either a low dose, a high dose, or a placebo to assess the impact on their exercise capacity. The study focuses on individuals aged 18-39 who have a high level of maximal oxygen consumption. The goal is to determine the efficacy of this treatment in enhancing exercise performance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18-39
* Physically active \> 5 h weekly
* Maximal oxygen consumption classified as high or very high

Exclusion Criteria:

* Diagnosed with severe asthma and been in treatment with long-acting beta2-agonist/corticosteroid
* ECG abnormality
* ACQ score \> 1.5
* Severe bronchial hyperreactivity as determined by mannitol test
* FEV1/FVC ratio \< 0.7 determined with spirometry
* Chronic illness determined to be a potential risk for participant during study
* In chronic treatment with medication that may interfere with study results
* Pregnancy
* Smoker
* Blood donation during the past 3 months

Where it's running

• August Krogh Building
  Copenhagen, Dk, Denmark Recruiting

Study contacts

• Principal investigator: Morten Hostrup, PhD — University of Copenhagen
• Study coordinator: Morten Hostrup, PhD
• Email: mhostrup@nexs.ku.dk
• Phone: +4535321595

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.