Effects of ultrasound therapy on median nerve function
Effect of Non-thermal Parameters of Ultrasound on Median Motor Nerve Conduction Velocity.
This study tests how different levels of ultrasound therapy can improve the function of the median nerve in healthy volunteers.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 120 (estimated) |
| Ages | 18 Years to 24 Years |
| Sex | All |
| Sponsor | Cairo University Academic / other |
| Locations | 1 site (Giza) |
| Trial ID | NCT05233488 on ClinicalTrials.gov |
What this trial studies
This study investigates how different doses of pulsed ultrasound therapy affect the conduction parameters of the median nerve in healthy volunteers. Participants will receive ultrasound treatment at varying intensities and duty cycles, and nerve conduction parameters such as latency, amplitude, area, duration, and forearm nerve conduction velocity will be measured before and after treatment. The goal is to determine the optimal ultrasound settings for improving nerve function.
Who should consider this trial
Good fit: Ideal candidates are healthy individuals aged 18 to 24 with no history of neurological or neuromuscular disorders affecting the upper limb.
Not a fit: Patients with conditions such as peripheral polyneuropathy, diabetes, or previous nerve surgeries will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved therapeutic approaches for treating entrapment neuropathies.
How similar studies have performed: While the use of ultrasound therapy in nerve treatment is established, the specific dosing and effects on median nerve conduction parameters are less explored, making this approach somewhat novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. 120 hands of 60 subjects of both genders with age range 18: 24 years. 2. Subjects assigned will be apparently healthy subjects with no neurological or neuromuscular history affecting the upper limb. Exclusion Criteria: 1. Peripheral polyneuropathy. 2. Diabetes mellitus. 3. Previous surgeries or median and/or ulnar nerve release. 4. Cervical radiculopathy. 5. Median or ulnar entrapment neuropathies. 6. Previous or current pregnancies.
Where this trial is running
Giza
- Cairo University — Giza, Egypt (Recruiting)
Study contacts
- Principal investigator: Amr S Shalaby, Ph.D. — Cairo University
- Study coordinator: Amr S Shalaby, Ph.D.
- Email: amr.saad@pt.cu.edu.eg
- Phone: 00201147718803
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.