Effects of Transcranial Magnetic Stimulation on Brain Blood Flow Regulation in Healthy Adults
Effect of Transcranial Magnetic Stimulation on Dynamic Cerebral Autoregulation in Healthy Adults
NA · The First Hospital of Jilin University · NCT05915923
This study tests how different types of brain stimulation can change blood flow regulation in healthy adults to see if it might help improve brain health in the future.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 18 Years to 59 Years |
| Sex | All |
| Sponsor | The First Hospital of Jilin University (other) |
| Locations | 1 site (Jilin) |
| Trial ID | NCT05915923 on ClinicalTrials.gov |
What this trial studies
This study investigates how different modes of transcranial magnetic stimulation (TMS) affect dynamic cerebral autoregulation in healthy adults. Participants will receive either 1 Hz or 10 Hz TMS, or a sham stimulation, to assess changes in cerebral blood flow regulation. The research aims to understand the neuroprotective effects of TMS, which may enhance blood supply to the brain and improve outcomes for conditions like ischemic stroke. By examining these effects in healthy individuals, the study seeks to establish a foundation for future applications in clinical populations.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy adults aged 18 to 60 who are willing to participate and provide informed consent.
Not a fit: Patients with chronic organic diseases, mental health disorders, or other specified conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new therapeutic strategies for improving brain blood flow regulation, potentially benefiting patients with ischemic stroke.
How similar studies have performed: While studies on TMS have shown promise in various neurological conditions, this specific approach to assessing dynamic cerebral autoregulation in healthy adults is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age≥18 years, \< 60 years, both genders； 2. Willing to participate and sign the informed consent； 3. Bilateral temporal windows were well penetrated; Exclusion Criteria: 1. Complaints of previous or existing chronic organic diseases ( stroke, Parkinson 's disease, hypertension, diabetes, etc. ), mental diseases ( bipolar disorder, personality disorder, schizophrenia, etc. ), or cognitive impairment; 2. Suffering from infectious diseases in late one month; 3. Pregnancy or breast-feeding; 4. Sleep disorders, anxiety and depression, 5. Alcohol or drug abuse; 6. History of prescription drugs or over-the-counter (OTC) drugs in the past 2 weeks; 7. History of epilepsy or family history of epilepsy; 8. Implants ( stents or metals ); 9. Other conditions that the researchers think are not suitable for the project.
Where this trial is running
Jilin
- The First Hospital of Jilin University — Jilin, China (RECRUITING)
Study contacts
- Study coordinator: Yi Yang, PhD
- Email: doctoryangyi@163.com
- Phone: 13756661217
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Transcranial Magnetic Stimulation, transcranial magnetic stimulation, healthy adults