Effects of Toric IOLs on Vision and Balance in Cataract Patients
Vision and Balance Changes After Bilateral Implantation of Toric Versus Non-Toric Intraocular Lenses in Cataract Patients With Astigmatism
This study is testing whether special lenses for cataract surgery can improve vision and balance in people with astigmatism to help them feel safer and live better.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 140 (estimated) |
| Ages | 50 Years to 75 Years |
| Sex | All |
| Sponsor | University of Plymouth Academic / other |
| Locations | 1 site (Plymouth) |
| Trial ID | NCT05629078 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of bilateral implantation of toric intraocular lenses (IOLs) on visual outcomes and dynamic stability in patients with cataracts and significant astigmatism. A total of 140 participants awaiting cataract surgery will be randomly assigned to receive either toric or standard non-toric IOLs. The study will assess balance and mobility through movement sensors and questionnaires at multiple time points before and after surgery. The goal is to determine if correcting astigmatism with toric IOLs improves quality of life and reduces the risk of falls.
Who should consider this trial
Good fit: Ideal candidates are individuals with bilateral significant corneal astigmatism greater than 1.0D who are on the waiting list for cataract surgery.
Not a fit: Patients with pre-existing eye conditions or those who have had previous eye surgeries may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance visual quality and balance in cataract patients, potentially reducing fall risks and improving overall quality of life.
How similar studies have performed: Previous studies have indicated that toric IOLs can improve visual outcomes in astigmatic patients, suggesting a positive outlook for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * bilateral significant corneal astigmatism \>1.0D * on waiting list for bilateral cataract surgery in NHS Exclusion Criteria: * pre-existing eye pathology which may be aggravated by intraocular implant * previous intraocular/ corneal surgery * History of uveitis, glaucoma, proliferative diabetic retinopathy or IDDM, pseudoexfoliation, macular degeneration that may affect potential best corrected visual acuity of 20/40 or better * Micropthalmia * corneal decompensation or endothelial insufficiency * pars planitis * high myopia * participants using a systematic medication that is known to cause ocular side effects * participated in a concurrent clinical trial or have participated in an opthalmology clinical trial within the last 30 days * unable or not willing to cooperate for the follow up period * pregnant women * unable to give informed consent * unable to walk with or without walking aids independently for at least 20m * unable to walk up/down stairs independently using aids or handrail
Where this trial is running
Plymouth
- Royal Eye Infirmary — Plymouth, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Nabil Habib, MB ChB(Hons) — Royal Eye Infirmay, University Hosptials Plymouth NHS Trust
- Study coordinator: Sherrie T Choy, MSc
- Email: sherrie.choy@plymouth.ac.uk
- Phone: 07903692005
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.