Effects of thickened feeds on infants with unexplained life-threatening events

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how thickened feeds impact clinical outcomes and healthcare utilization in infants who have experienced brief resolved unexplained events (BRUE). BRUE episodes can be alarming and are often associated with oropharyngeal dysphagia, which may contribute to ongoing symptoms. The study will follow a cohort of infants receiving thickened feeds compared to those on non-thickened feeds over the course of one year to assess the potential benefits of this intervention. The goal is to better understand the relationship between feeding modifications and the management of BRUE.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Less than 1 year of age
* Admitted to Boston Children's Hospital after experiencing first lifetime brief resolved unexplained event.

Exclusion Criteria:

* Any pre-existing medical diagnoses that exclude brief resolved unexplained event diagnosis including seizure disorders and cyanotic congenital heart disease
* Already receiving thickened liquids for treatment of another condition

Where it's running

• Boston Children's Hospital
  Boston, Massachusetts, United States Recruiting

Study contacts

• Principal investigator: Daniel R Duncan, MD, MPH — Boston Children's Hospital
• Study coordinator: Daniel R Duncan, MD, MPH
• Email: daniel.duncan@childrens.harvard.edu
• Phone: 6173550897

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.