Effects of resistance training on the nervous system in healthy individuals

Adaptive Response of Brain Towards Resistance Training in Healthy Individuals

Not applicable Interventional Pakistan Society for Rehabilitation of Differently Abled Hospital · NCT06413199

This study tests how resistance training affects the nervous system in healthy people to see if it helps them get stronger.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages18 Years to 35 Years
SexAll
SponsorPakistan Society for Rehabilitation of Differently Abled Hospital Academic / other
Locations1 site (Lahore, Punjab Province)
Trial IDNCT06413199 on ClinicalTrials.gov

What this trial studies

This study investigates how resistance training impacts the central and peripheral nervous systems in healthy individuals. A total of 100 participants, both male and female, will be divided into an experimental group performing specific resistance training exercises and a control group measuring their one-repetition maximum (1RM). The experimental group will engage in a structured training regimen over two months, focusing on both concentric and eccentric contractions. The goal is to understand the underlying mechanisms of the nervous system's adaptation to resistance training.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals with a BMI between 18.5 and 24.9 who have not engaged in resistance training for at least six months.

Not a fit: Patients with gastrointestinal, musculoskeletal, or neurological disturbances, as well as those using tobacco or medications, may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of how resistance training influences nervous system function, potentially leading to improved training protocols for athletes and fitness enthusiasts.

How similar studies have performed: While the specific mechanisms of nervous system adaptation to resistance training are still being explored, similar studies have shown promising results in understanding the benefits of exercise on neurological function.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Body Mass Index should be 18.5-24.9 kg/m2.
* Participants were untrained and had not engaged in resistance exercise within 6 months prior to beginning the study.

Exclusion Criteria:

* Participants with any kind of Gastrointestinal Tract disturbance will be excluded from the study.
* Participants with any kind of Musculoskeletal injury will be excluded from the study.
* Participant with any kind of Neurological disturbance will be excluded from the study.
* Participants who use tobacco products within the previous 6 months.
* Participants who take any type of medication within the previous 6 months.

Where this trial is running

Lahore, Punjab Province

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Resistance TrainingPerformanceNervous ResponseMuscle growthExercise Induced Performance
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.