Effects of resistance training on nervous system function in multiple sclerosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of progressive resistance training on corticospinal excitability and walking capacity in individuals with multiple sclerosis (pwMS). A total of 54 participants will be randomized into three groups: high dose resistance training, low dose resistance training, and a waitlist control group. The study aims to explore how resistance training can improve neuromuscular function and potentially enhance quality of life for pwMS. The methodology includes the use of non-invasive brain stimulation techniques to assess changes in central nervous system functioning.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥ 18 years
* MS diagnosis according to the McDonald diagnostic criteria
* Shows impairments in walking capacity
* Ability to self transport to test and exercise

Exclusion Criteria:

* Pregnancy
* Neurological or other comorbidities that affects the nervous system
* Relapse within the past 2 months
* Pacemaker or metallic implants
* Hypertension (medically unregulated)
* Participation in structured RT over the past 3 months (≥ 2 sessions/week).

Where it's running

• Department of Public Health
  Aarhus, Central Jutland, Denmark Recruiting
• Department of Nutrition, Exercise and Sports, University of Copenhagen
  Copenhagen, Copenhagen N, Denmark Recruiting

Study contacts

• Study coordinator: Lars Hvid, PhD
• Email: lhvid@ph.au.dk
• Phone: 93508717

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.