Effects of Remimazolam on Brain Activity in Children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study investigates how Remimazolam anesthesia affects brain electrical activity in children aged 1 to 12 years. Participants will be grouped by age and monitored for changes in electroencephalography (EEG) during anesthesia induction, maintenance, and recovery. The study aims to identify specific EEG patterns associated with Remimazolam, which may improve monitoring techniques for anesthesia depth in pediatric patients. Informed consent will be obtained from parents or legal guardians prior to participation.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1\. aged 1 years-12 years; 2, with American Society of Anesthesiologists (ASA) physical status I or II; 3, children requiring general anesthesia under remimazolam; 4, parents or legal guardians of children who volunteered to participate in the trial; And signed the informed consent form.

Exclusion Criteria:

1. Congenital malformation or other genetic conditions that are thought to affect brain development ;
2. History of severe heart, brain, liver, kidney and metabolic diseases ;
3. Premature infants (≤32 weeks);
4. Upper respiratory tract infection in the last two weeks. -

Where it's running

• The second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
  Wenzhou, Zhejiang, China Recruiting

Study contacts

• Principal investigator: Huacheng Liu — Second Affiliated Hospital of Wenzhou Medical University
• Study coordinator: Huacheng Liu
• Email: huachengliu@163.com
• Phone: 13957770577

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Personalized dosing of remimazolam during general anesthesia using the Eleveld PK/PD model

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• Patient-controlled remimazolam sedation under spinal anesthesia for hip replacement

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• Remimazolam effects on brain activity, pain response, and memory during MRI

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  Recruiting Early Phase 1 University of Pittsburgh · Pittsburgh, Pennsylvania · NCT07290205

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.