Effects of Platelet-rich Plasma on Sperm Quality After Freezing
The Effects of Autologous Platelet-rich Plasma Supplement During Sperm Cryopreservation
This study is testing if adding platelet-rich plasma to frozen sperm samples can improve their quality after thawing for men who are looking to preserve their fertility.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | Male |
| Sponsor | Department of Medical Services Ministry of Public Health of Thailand Government |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT06258759 on ClinicalTrials.gov |
What this trial studies
This study investigates the impact of adding autologous platelet-rich plasma (PRP) to sperm samples during the cryopreservation process. Participants will provide semen samples that will be divided into two groups: one with PRP supplementation and a control group without it. Both groups will undergo sperm vitrification for 14 days, after which the samples will be thawed and analyzed for quality metrics such as motility and DNA fragmentation. The aim is to determine if PRP can enhance post-cryopreservation sperm quality.
Who should consider this trial
Good fit: Ideal candidates are healthy men aged 20-40 with normal semen analysis who can communicate in Thai.
Not a fit: Patients diagnosed with infertility or any hematological disorders will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve sperm viability and quality for men undergoing cryopreservation.
How similar studies have performed: While the use of PRP in various medical applications is gaining traction, this specific approach to sperm cryopreservation is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. A man who be a Rajavithi hospital clients or staff. 2. Aged 20-40 years old. 3. Has normal semen analysis. 4. Can communicate and understand Thai language very well. 5. Voluntarily participated in the research. 6. Sexual abstinence for 2-7 days. Exclusion Criteria: 1. A man who ever diagnosed with infertile patient. 2. A wan who diagnosed with any hematological disease such as Coagulation disorders, Hypertension, Thrombocytopenia, Platelet dysfunction.
Where this trial is running
Bangkok
- Rajavithi hospital — Bangkok, Thailand (Recruiting)
Study contacts
- Study coordinator: Choermin Thitipatlertdech, M.D.
- Email: choermin@hotmail.com
- Phone: +6692-2659265
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.