Effects of physical therapy and platelet-rich plasma on knee ligament injuries
Effect of Physical Therapy and/or Platelet Rich Plasma Injection in People With Knee Cruciate Ligament Injuries: an Observative Study
This study is testing if physical therapy and platelet-rich plasma injections can help people with knee ligament injuries feel better and move more easily without surgery.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 40 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Taipei Hospital, Ministry of Health and Welfare Academic / other |
| Locations | 1 site (New Taipei City) |
| Trial ID | NCT06233305 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of physical therapy and platelet-rich plasma (PRP) injections on individuals with injuries to the anterior and posterior cruciate ligaments. It aims to assess the outcomes of these interventions in improving knee stability, reducing pain, and enhancing joint function. Participants will be evaluated based on MRI findings and their response to non-surgical treatments. The study focuses on individuals who have not undergone any surgical interventions for their knee injuries.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 to 80 with partial tears of the anterior or posterior cruciate ligaments confirmed by MRI.
Not a fit: Patients with severe knee joint damage requiring surgical intervention or those with pre-existing knee joint diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a non-surgical treatment option that significantly improves recovery and quality of life for patients with knee ligament injuries.
How similar studies have performed: Previous studies have shown promising results with PRP injections in improving knee function and reducing pain, indicating that this approach has potential based on existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age between 18 to 80 years old. 2. Magnetic Resonance Imaging (MRI) shows partial tearing of the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL), possibly combined with injuries to the medial collateral ligament (MCL) or meniscus. 3. No surgical treatment has been undergone. Exclusion Criteria: 1. Had knee joint diseases or undergone knee joint surgery before the injury. 2. Surgical intervention is required for severe damage to knee joint ligaments, meniscus, or articular tissues, such as complete rupture of lateral ligaments or full-thickness cartilage injuries. 3. Suffers from diseases affecting physical activity function, such as stroke or nerve damage.
Where this trial is running
New Taipei City
- Taipei Hospital, Ministry of Health and Welfare — New Taipei City, Taiwan (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.