Effects of physical therapy and platelet-rich plasma on knee ligament injuries

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of physical therapy and platelet-rich plasma (PRP) injections on individuals with injuries to the anterior and posterior cruciate ligaments. It aims to assess the outcomes of these interventions in improving knee stability, reducing pain, and enhancing joint function. Participants will be evaluated based on MRI findings and their response to non-surgical treatments. The study focuses on individuals who have not undergone any surgical interventions for their knee injuries.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age between 18 to 80 years old.
2. Magnetic Resonance Imaging (MRI) shows partial tearing of the anterior cruciate ligament (ACL) or posterior cruciate ligament (PCL), possibly combined with injuries to the medial collateral ligament (MCL) or meniscus.
3. No surgical treatment has been undergone.

Exclusion Criteria:

1. Had knee joint diseases or undergone knee joint surgery before the injury.
2. Surgical intervention is required for severe damage to knee joint ligaments, meniscus, or articular tissues, such as complete rupture of lateral ligaments or full-thickness cartilage injuries.
3. Suffers from diseases affecting physical activity function, such as stroke or nerve damage.

Where it's running

• Taipei Hospital, Ministry of Health and Welfare
  New Taipei City, Taiwan Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.