Effects of oxygen therapy on decompression sickness in divers

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of hyperoxia and the immune system's role in decompression sickness, particularly focusing on the effects of hyperbaric oxygen therapy. It aims to understand how oxygen levels influence the development of decompression sickness during diving and the subsequent treatment with normobaric and hyperbaric oxygen. The research involves healthy subjects and patients suspected of diving accidents, utilizing diving simulations to assess the physiological responses. The study will analyze circulating mitochondrial DNA levels to explore cellular damage associated with hyperoxia.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy subject with no contraindications to diving OR patient admitted to the hospital for suspicion of a diving accident OR patient admitted to the hospital for hyperbaric oxygen therapy

Exclusion Criteria:

* Contraindication to diving or contraindication to hyperbaric oxygen therapy

Where it's running

• Hôpital d'Instruction des Armées Sainte-Anne
  Toulon, France Recruiting

Study contacts

• Study coordinator: Nicolas VALLEE, PhD
• Email: nicolas.vallee@intradef.gouv.fr
• Phone: 483162849

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.