Effects of nicotine pouch characteristics on user perceptions and behavior
Effect of Product Characteristics on the Appeal and Sensory Attributes of Nicotine Pouches
This study tests how different strengths and flavors of nicotine pouches affect how young adults feel about them and whether they want to keep using them.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 72 (estimated) |
| Ages | 21 Years to 35 Years |
| Sex | All |
| Sponsor | University of Southern California Academic / other |
| Locations | 2 sites (Los Angeles, California and 1 other locations) |
| Trial ID | NCT06597435 on ClinicalTrials.gov |
What this trial studies
This study investigates how different nicotine concentrations and pH levels in nicotine pouches affect sensory attributes and product appeal among young adult users aged 21-35 who are currently using nicotine pouches. Participants will undergo an experimental session where they will self-administer various nicotine pouches and provide feedback on their experiences. The study aims to understand the appeal of these products, particularly among those who are unmotivated to quit nicotine use. By assessing these factors, the research seeks to inform regulatory approaches to nicotine pouch products.
Who should consider this trial
Good fit: Ideal candidates for this study are young adults aged 21-35 who are current users of nicotine pouches and are unmotivated to quit.
Not a fit: Patients who intend to quit nicotine use within the next 30 days or those with certain health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights that help regulate nicotine pouch products to minimize potential harm to users.
How similar studies have performed: While there is limited research specifically on nicotine pouches, studies on similar tobacco products have shown varying degrees of success in understanding user behavior and perceptions.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults age 21-35 years old. * Current nicotine pouch users (used nicotine pouches in the past 30 days). Current dual users of nicotine pouches and e-cigarettes and/or combustible cigarettes will be eligible. * Positive cotinine test via saliva test strip. * Unmotivated to quit nicotine use. * English language competency (read and speak English). The instruments used have not been translated and/or validated for other languages. Exclusion Criteria: * Intention to quit nicotine use in the next 30 days. * Current pregnancy or breastfeeding (urine pregnancy test will be conducted during the orientation session). * History of stroke, seizures, high blood pressure (hypertension), heart disease/problems, lung disease/lung problems, or cardiovascular disease contraindications for nicotine. * People under 21 years will be excluded to correspond with the legal age for purchasing tobacco products in the United States. Special subject populations will not be recruited.
Where this trial is running
Los Angeles, California and 1 other locations
- University of Southern California — Los Angeles, California, United States (Not_yet_recruiting)
- University of Southern California - Clinical Sciences Building — Los Angeles, California, United States (Recruiting)
Study contacts
- Principal investigator: Dae Hee Han, PhD — University of Southern California
- Study coordinator: Dae Hee Han, PhD
- Email: daeheeha@usc.edu
- Phone: 626-200-8334
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.