Effects of nerve blocks on pain management after kidney donation surgery
Effects of Combined Rectus Sheath and Ilioinguinal Nerve Block on Opioid Consumption in Hand-Assisted Laparoscopic Donor Nephrectomy Patients: A Randomized Controlled Double-Blind Prospective Study
This study is testing if using special nerve blocks can help kidney donors manage pain better after surgery and reduce their need for opioids.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Koç University Academic / other |
| Locations | 1 site (Istanbul, Zeytinburnu) |
| Trial ID | NCT06941259 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the effectiveness of combined rectus sheath and ilioinguinal nerve blocks for pain management in patients undergoing hand-assisted laparoscopic donor nephrectomy. It aims to determine if these regional anesthesia techniques can reduce postoperative opioid consumption and related side effects compared to a placebo group. Participants will be randomly assigned to receive either the nerve blocks with local anesthesia or a sham block, and their opioid use will be monitored for 24 hours post-surgery. The study employs a double-blind design to ensure unbiased results.
Who should consider this trial
Good fit: Ideal candidates are individuals approved for laparoscopic hand-assisted donor nephrectomy who do not have contraindications for the nerve blocks.
Not a fit: Patients with chronic narcotic use, psychiatric disorders, or severe physical status (ASA III and above) may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce opioid consumption and its associated side effects in kidney donors.
How similar studies have performed: Previous studies have shown promising results with similar regional anesthesia techniques in reducing opioid use, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * The donors reviewed by the transplant committee and deemed suitable for nephrectomy. * Laparoscopic hand assisted donor nephrectomy operation is planned. Exclusion Criteria: * Allergy to any of the drugs to be used in treatment * Patients using chronic narcotics or narcotic receptor agonists * Patients with psychiatric disorders * Patients with chronic organ failure * Patients without end organ damage * The patients who did not give consent * Foreign national patients * Patients with American Society of Anaesthesiologists (ASA) physical status classification score III and above
Where this trial is running
Istanbul, Zeytinburnu
- Koç University Hospital — Istanbul, Zeytinburnu, Turkey (Recruiting)
Study contacts
- Principal investigator: Yasemin Sincer, MD — Koç University
- Study coordinator: Yasemin Sincer, MD
- Email: ysincer@kuh.ku.edu.tr
- Phone: +90 531 204 08 34
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.