Effects of Nasal High Flow Therapy on Asthma Symptoms
Influence of Nasal High-flow Therapy (NHFT) on Ventilation and Sympathetic Drive in Patients With Asthma
This study is testing if Nasal High Flow Therapy can help people with asthma breathe better by looking at how it affects their nerve activity.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | RWTH Aachen University Academic / other |
| Locations | 1 site (Aachen, NRW) |
| Trial ID | NCT05704101 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the impact of Nasal High Flow Therapy (NHFT) on sympathetic nerve activity (SNA) in patients with asthma. Conducted at the RWTH Aachen University Hospital, the study aims to explore the relationship between SNA overactivity and asthma, a condition affecting millions globally. By utilizing advanced techniques, the researchers will assess respiratory muscle function and the potential benefits of NHFT, which has shown promise in improving breathing mechanics in other pulmonary diseases. The study seeks to fill a gap in understanding how NHFT may alleviate symptoms in asthma patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older with a clinically diagnosed case of asthma.
Not a fit: Patients with pre-existing cardiovascular diseases or other significant pulmonary conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for asthma patients through the use of NHFT.
How similar studies have performed: While NHFT has shown benefits in conditions like COPD, comprehensive studies specifically targeting asthma are still limited, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Clinically diagnosed Asthma * Age ≥ 18 * Ability and willingness to give informed consent to participate in the study Exclusion Criteria: * Atrial fibrillation * Active pacing of the heart by a cardiac pacemaker (i.e. no intrinsic heart rate) * Clinically pre-established cardiovascular disease or other pulmonary diseases (e.g. arterial hypertension, systolic heart failure, COPD) * In-patient stay in the hospital within the last 4 weeks prior to the study examination date * Severe polyneuropathy
Where this trial is running
Aachen, NRW
- University Hospital RWTH Aachen-Department of Pneumology and Intensive Care — Aachen, Nrw, Germany (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.