Effects of music on seizures in children with epilepsy

Effects of Recorded Music on Clinical and Electroencephalography (EEG) Seizure Activity

NA · Johns Hopkins University · NCT05289934

This study is testing if listening to Mozart and other fun songs can help reduce seizures in children with epilepsy aged 4 to 17.

Quick facts

PhaseNA
Study typeInterventional
Enrollment10 (estimated)
Ages4 Years to 17 Years
SexAll
SponsorJohns Hopkins University (other)
Locations1 site (Baltimore, Maryland)
Trial IDNCT05289934 on ClinicalTrials.gov

What this trial studies

This research investigates whether listening to Mozart's music and age-appropriate songs can reduce seizure frequency and epileptiform discharges in children with epilepsy. The study will involve children aged 4 to 17 years who will listen to selected music during their stay in an Epilepsy Monitoring Unit (EMU). The music will be played randomly over several days while continuous video electroencephalography (EEG) monitors their brain activity. The goal is to determine if there are significant differences in seizure activity when exposed to different types of music compared to baseline measurements.

Who should consider this trial

Good fit: Ideal candidates are children aged 4 to 17 years who are admitted to an Epilepsy Monitoring Unit for observation.

Not a fit: Patients who do not speak English may not benefit from this study due to communication barriers.

Why it matters

Potential benefit: If successful, this study could provide a non-invasive therapeutic option for reducing seizure frequency in children with epilepsy.

How similar studies have performed: Previous studies have shown positive effects of Mozart music on seizure activity, suggesting this approach may be promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Children (age: 4 - 17 years old) who stay at Epilepsy Monitoring Units (EMU) up to 7 days may join.

Exclusion Criteria:

* Non-English Speaking

Where this trial is running

Baltimore, Maryland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Epilepsy, Electroencephalography, Music

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.