Effects of morning vs evening exercise on blood pressure in older women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates how the timing of exercise—either in the morning or early evening—affects blood pressure and vascular health in postmenopausal women with hypertension. Participants will undergo a 6-week exercise training program, with assessments of blood pressure and vascular function before and after the training. The research aims to explore the potential benefits of aligning exercise with the body's natural rhythms to improve cardiovascular health. This approach builds on previous findings that evening medication may be more effective for managing hypertension.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Systolic BP equal to or greater than 130 mmHg without BP medication or greater than 120 mmHg with medication and diastolic blood pressure equal to and greater than 80 mmHg
* 55-80 years old
* Post-menopausal female
* Able to walk without assistance

Exclusion Criteria:

* Habitually physically active defined as 150 minutes of moderate-intensity or 75 minutes of vigorous-intensity aerobic physical activity per week
* Overt pulmonary disease/condition as follows: chronic bronchitis, chronic obstructive pulmonary disease, emphysema, or pulmonary hypertension
* Cardiometabolic disease/condition as follows: diabetes, heart failure, peripheral arterial disease, stroke, coronary artery disease, renal disease, secondary hypertension, chronic venous insufficiency or deep vein thrombosis within last 6 months
* Cancer within last 5 years
* Body mass index \>39 kg/m2
* Current smoking or vape
* Evening shift work
* uncontrolled thyroid disorder
* 2 or more falls in the last year
* Anemia within 3 months of enrollment
* Parkinson's disease
* Dementia
* Unstable angina
* Acute pulmonary embolus or infarction
* Acute myocarditis or pericarditis
* Acute aortic dissection

Where it's running

• Michigan State University
  East Lansing, Michigan, United States Recruiting

Study contacts

• Study coordinator: Jill Slade, PhD
• Email: jslade@msu.edu
• Phone: 5178843351

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.