Effects of Methylphenidate on Motor Performance in Young Adults with ADHD
The Effects of a Single Dose of Methylphenidate on Motor Performance
PHASE4 · Loewenstein Hospital · NCT04283604
This study tests if a single dose of a common ADHD medication can help young adults with ADHD improve their motor skills compared to those without ADHD.
Quick facts
| Phase | PHASE4 |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | All |
| Sponsor | Loewenstein Hospital (other) |
| Locations | 1 site (Netanya) |
| Trial ID | NCT04283604 on ClinicalTrials.gov |
What this trial studies
This study evaluates how a single dose of methylphenidate (MPH) affects motor performance in young adults diagnosed with ADHD compared to a control group without ADHD. The research involves 200 participants, including 100 diagnosed with ADHD and 100 healthy individuals, who will undergo various motor tests across two sessions. Participants will perform these tests either with or without their usual ADHD medication, allowing for a comparison of performance under different conditions. The study aims to determine if MPH enhances motor skills that require concentration.
Who should consider this trial
Good fit: Ideal candidates are young adults aged 18-45 diagnosed with ADHD and currently treated with methylphenidate.
Not a fit: Patients with chronic illnesses other than ADHD or those taking chronic medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into optimizing treatment for ADHD patients to improve their motor performance.
How similar studies have performed: Previous studies have shown mixed results regarding the effects of MPH on motor performance, making this approach both relevant and exploratory.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Students age 18-45 years old studying at the academic college at Wingate. For the treatment group we will recruit students who were previously diagnosed by a neurologist or psychiatrist or other ADHD physician specialist as having ADHD, and are treated with a methylphenidate (Ritalin; Ritalin SR; Ritalin LA; Concerta) at least 3 months before the first session. Control group will consist of students without ADHD. Exclusion Criteria: any chronic illness other than ADHD (e.g. asthma, gastrointestinal, depression, anxiety, etc.), taking chronic medications apart from stimulant therapy.
Where this trial is running
Netanya
- Sharon Tsuk — Netanya, Israel (RECRUITING)
Study contacts
- Study coordinator: Aviva Mimouni-Bloch, MD
- Email: abloch@clalit.org.il
- Phone: 7709085
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: ADHD, Concerta, Physical Activity, Motor test, Exercise, Ritalin