Clinical trial Recruiting at 1 site Interventional Ages 18 and up Women only

Effects of menstrual cycle-based resistance training on female athletes' performance

Official title: Effects of Menstrual Cycle-based Undulating Periodized Resistance Training in Women's Neuromuscular Abilities

Run by Universite de La Reunion · NCT06679491 · Data updated 2026-11-12

This study tests if resistance training that changes with the menstrual cycle can improve strength and performance in female athletes compared to those using birth control.

Quick facts

Study typeInterventional
Ages18 Years and up
SexWomen only
Enrollment60 (estimated)
SponsorUniversite de La Reunion
Academic / other
Locations1 site (Le Tampon, France)
StatusRecruiting
StartedNovember 1, 2024
Main results expectedJuly 1, 2025
Study endsDecember 31, 2027
Registry record updatedNovember 7, 2024
Trial IDNCT06679491 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are recreationally active female athletes aged 18 and older with regular menstrual cycles.

Probably not a fit

Patients who may not benefit include those with irregular menstrual cycles or those not engaged in regular physical activity.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates how resistance training tailored to different phases of the menstrual cycle affects neuromuscular performance in female athletes. Participants will engage in a 13-week program with two training sessions per week, where the intensity of resistance training is adjusted based on their menstrual phase. The study compares the effects of training in natural menstrual cycle groups against a control group using oral contraceptives, focusing on outcomes such as knee extensor strength and muscle performance metrics. Neuromuscular assessments will be conducted before and after the intervention to evaluate the impact of the training protocols.

Why it matters

Potential benefit: If successful, this study could enhance training effectiveness and performance in female athletes by optimizing resistance training according to menstrual cycle phases.

How similar studies have gone: While there is limited research specifically on menstrual cycle-based resistance training, similar studies have shown that hormonal fluctuations can impact athletic performance, suggesting potential for success in this approach.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Female athletes with natural menstrual cycles (eumenorrheic): Participants must have regular menstrual cycles lasting between 21 and 35 days, with at least 9 cycles per year.
* Women using a low-dose monophasic estrogen-progestin oral contraceptive.
* Age 18 or older: Participants must be legal adults.
* Body Mass Index (BMI) between 18 and 30 kg/m².
* No medical contraindications to high-level physical training or exercise.
* Physically active: Engages in at least 3 hours of physical activity per week.
* Informed consent: Provides written, informed consent to participate in the study.
* Affiliation with a social security system (if applicable by local regulations).

Exclusion Criteria:

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Where it's running

  • Laboratoire IRISSE (Université de La Réunion)
    Le Tampon, France, Reunion
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.