Effects of liposomal vitamin C on absorption and metabolism
Effects of Liposomal Encapsulation on Vitamin C Absorption and Metabolism
This study is testing if a special form of vitamin C called liposomal vitamin C is better absorbed and used by healthy adults compared to regular vitamin C.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 20 Years to 60 Years |
| Sex | All |
| Sponsor | National Yang Ming Chiao Tung University Academic / other |
| Locations | 1 site (Taipei, Beitou Dist.) |
| Trial ID | NCT06372171 on ClinicalTrials.gov |
What this trial studies
This trial investigates how liposomal encapsulation affects the absorption and metabolism of vitamin C in healthy adults. It consists of a pre-trial screening phase followed by a two-stage open crossover design where participants will undergo two separate trials with a 14-day washout period in between. Participants will be screened for eligibility through general examinations and blood biochemical tests to ensure they meet specific health criteria. The goal is to determine if liposomal vitamin C can enhance bioavailability compared to traditional forms.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 20-60 without major organic diseases who can fully cooperate with the trial.
Not a fit: Patients with renal insufficiency, cancer, or those on chronic medications are unlikely to benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved vitamin C supplementation methods, enhancing antioxidant intake for various populations.
How similar studies have performed: While the concept of liposomal encapsulation is established, this specific application for vitamin C absorption is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults aged 20-60 years old, without heart, liver, kidney, endocrine or major organic diseases (patient report), and able to fully cooperate with the experiment. Exclusion Criteria: 1. Patients with renal insufficiency and dialysis 2. Cancer patients 3. Underweight (BMI≦17) or obese (BMI≧27) 4. Those taking medications for chronic diseases 5. Blood pressure systolic blood pressure ≧ 130 mmHg or diastolic blood pressure ≧ 85 mmHg 6. Fasting blood glucose ≧ 100 mg/dL 7. Fasting triglycerides ≧ 150 mg/dL, total cholesterol ≧ 200 mg/dL 8. Have a history of vitamin C allergy 9. People suffering from mental illness 10. Pregnant and breastfeeding women 11. Patients with hemosiderosis 12. Kidney stone patients 13. People who take vitamin C for a long time should take supplements (at least 200 mg per day for more than one month)
Where this trial is running
Taipei, Beitou Dist.
- National Yang Ming Chiao Tung University — Taipei, Beitou Dist., Taiwan (Recruiting)
Study contacts
- Study coordinator: ChienYu Huang, Bachelor
- Email: chienyu.ns11@nycu.edu.tw
- Phone: +886-955-879163
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.