Effects of L-arginine on exercise performance
The Effects of L-arginine Supplementation on Anaerobic Exercise Performance
This study is testing if taking L-arginine can help young, healthy adults perform better during short bursts of exercise compared to a placebo.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 39 Years |
| Sex | All |
| Sponsor | University of Manitoba Academic / other |
| Locations | 1 site (Winnipeg, Manitoba) |
| Trial ID | NCT06475391 on ClinicalTrials.gov |
What this trial studies
This study evaluates whether acute ingestion of L-arginine can enhance anaerobic exercise performance in young, healthy, recreationally active adults. Participants will undergo a randomized, double-blind, placebo-controlled, cross-over design, where they will complete two exercise sessions after ingesting either L-arginine or a placebo. Measurements will include body composition, resting blood pressure, and various performance metrics such as grip strength and jump height. A one-week wash-out period will separate the two testing sessions to ensure accurate comparisons.
Who should consider this trial
Good fit: Ideal candidates are recreationally active individuals aged 18-39 who exercise at least three times a week.
Not a fit: Patients with cardiovascular, metabolic, neurological, or psychological diseases, as well as smokers and those on medication, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into nutritional supplementation that enhances athletic performance in young adults.
How similar studies have performed: While the effects of L-arginine on exercise performance have been explored, this specific approach using a double-blind, placebo-controlled design is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Recreationally physically active individuals will be recruited for the study. In this context it means all participants perform 1-hour of exercise per day over 3-days per week at a minimum for 1-month. All participants will be between the ages of 18-39 years of age. Exclusion Criteria: * Exclusion criteria for the study includes: 1) smokers; 2) unhealthy (have cardiovascular, metabolic, neurological, or psychological disease); 3) taking medication for any condition; 4) any known allergy to the supplements of interest (L-arginine or placebo \[dextrose\]).
Where this trial is running
Winnipeg, Manitoba
- Applied Research Centre; Active Living Centre — Winnipeg, Manitoba, Canada (Recruiting)
Study contacts
- Study coordinator: Stephen M Cornish, PhD
- Email: Stephen.Cornish@umanitoba.ca
- Phone: 204-381-7296
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.