Effects of Keratinized Mucosa Augmentation on Peri-implant Mucositis Treatment
Impact of Keratinized Mucosa Augmentation Following Non-surgical Therapy on Treatment Outcomes of Peri-implant Mucositis.
This study is testing if adding more gum tissue around dental implants can help treat gum inflammation in people with different levels of gum health.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 48 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Biruni University Academic / other |
| Locations | 1 site (Istanbul) |
| Trial ID | NCT06305000 on ClinicalTrials.gov |
What this trial studies
This study evaluates the impact of increasing the width of keratinized mucosa using free gingival grafts on the treatment outcomes of peri-implant mucositis. It involves four groups of participants: those with healthy peri-implant tissues, those with mucositis and sufficient keratinized mucosa, those with mucositis and insufficient keratinized mucosa receiving only non-surgical treatment, and those with insufficient keratinized mucosa receiving both non-surgical treatment and free gingival grafts. Clinical and biochemical parameters will be assessed at multiple time points to determine the effectiveness of the interventions.
Who should consider this trial
Good fit: Ideal candidates include individuals with dental implants that have been functional for at least one year and who meet specific health criteria.
Not a fit: Patients with active periodontal disease, autoimmune conditions, or those who smoke heavily may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could improve treatment outcomes for patients suffering from peri-implant mucositis.
How similar studies have performed: While the specific approach of using free gingival grafts for this condition may be novel, similar studies have shown promising results in improving peri-implant health.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individual dental implants with a fixed prosthetic restoration that has been functional for at least 1 year * No systemic disease and medication use that may affect periodontal or peri-implanter tissues * Not receiving periodontal treatment in the last 6 months * Volunteering to participate in the study Exclusion Criteria: * Prosthetic restorations with an excessive contour which do not allow peri-implant pocket measurement * Being pregnant or breastfeeding, * Autoimmune and/or inflammatory diseases of the oral cavity, * Active periodontal disease * Smokers (≥ 10 cigarettes per day) * Improperly positioned implants
Where this trial is running
Istanbul
- Biruni University — Istanbul, Turkey (Türkiye) (Recruiting)
Study contacts
- Principal investigator: Ayse E Selman — Biruni University
- Study coordinator: Ayse E Selman
- Email: aselman@biruni.edu.tr
- Phone: +905366393184
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.