Effects of intermittent hypoxia on limb functions in people with incomplete spinal cord injury
Effects of Device Induced Acute Intermittent Hypoxia in Upper and Lower Limb Activity Functions in Persons With Incomplete Spinal Cord Injury.
NA · Riphah International University · NCT05491837
This study tests if short periods of low oxygen can help improve movement in the arms and legs of people with incomplete spinal cord injuries.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 68 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Riphah International University (other) |
| Locations | 1 site (Islamabad) |
| Trial ID | NCT05491837 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates the impact of acute intermittent hypoxia on improving upper and lower limb functions in individuals with incomplete spinal cord injuries. The study employs a randomized controlled design with triple blinding to ensure unbiased results. Participants will receive either intermittent hypoxia or normoxia treatments, and their functional recovery will be assessed through various measures. The trial aims to enhance neuroplasticity and functional recovery in this population, addressing a significant gap in rehabilitation strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 18 and older with incomplete spinal cord injuries classified as ASIA category C or D.
Not a fit: Patients with complete spinal cord injuries or those with unstable orthopedic conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve mobility and quality of life for patients with incomplete spinal cord injuries.
How similar studies have performed: While the concept of using intermittent hypoxia to enhance neuroplasticity is promising, this specific approach in the context of incomplete spinal cord injury is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Incomplete SCI≥ 3 months(21); 2. Traumatic and non-traumatic, non-progressive lesions, Aged ≥ 18 years ; 3. LesionC4 and below as classified ASIA category C and D; 4. Both gender 5. Ability to ambulate with or without assistive devices; and 6. Ability to follow verbal and visual command. Exclusion Criteria: 1. Participants with complete spinal cord injury; 2. Unstable orthopedic injuries and joint contractures 3. Osteoporosis with high risk of fracture; 4. Pressure ulcers and cutaneous lesion(4) 5. Cognitive impairment, severe cardiopulmonary complication such as severe breathing disorder
Where this trial is running
Islamabad
- Riphah International University Islamabad — Islamabad, Pakistan (RECRUITING)
Study contacts
- Principal investigator: Ikram Ali, Master — Riphah International University Islamabad
- Study coordinator: Ikram Ali, Master
- Email: drikramali@gmail.com
- Phone: 00923343475727
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Incomplete Spinal Cord Injury