Effects of hot and cold baths on health and adaptation

Time Course of Adaptive Responses in Humans During a 16-day Hot and Cold Acclimation Program, and Its Effect on Health-related Indicators

Not applicable Interventional Lithuanian Sports University · NCT06346639

This study tests if taking hot and cold baths for 16 days can help improve how our bodies adapt to temperature changes and boost our overall health.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment31 (estimated)
Ages18 Years to 45 Years
SexAll
SponsorLithuanian Sports University Academic / other
Locations1 site (Kaunas)
Trial IDNCT06346639 on ClinicalTrials.gov

What this trial studies

This study investigates the impact of a 16-day regimen of whole-body immersion in hot and cold baths on the body's adaptive responses and health-related indicators. The primary goal is to assess whether these thermal interventions can enhance heat and cold adaptation by remodeling thermoregulatory, metabolic, cardiovascular, and physiological responses. Additionally, the study aims to evaluate any potential effects on physical and mental health markers resulting from the acclimation process.

Who should consider this trial

Good fit: Ideal candidates for this study are young, healthy, non-obese males and females who do not smoke and are not taking medications that could influence the outcomes.

Not a fit: Patients with neurological, cardiovascular, metabolic, or inflammatory diseases, or those involved in temperature manipulation programs or excessive physical exercise may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into how thermal acclimation can improve overall health and adaptive responses in individuals.

How similar studies have performed: There have been no previous studies specifically examining the combined effects of hot and cold baths on adaptive responses, making this approach novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* young, healthy, non-obese males and females;
* nonsmoker;
* no needle phobia;
* not taking medication and/or dietary supplements that may affect experimental variables.

Exclusion Criteria:

* neurological, cardiovascular, metabolic, and/or inflammatory diseases, or conditions that could be worsened by exposure to acute thermal stimuli and that could affect experimental variables;
* involvement in temperature manipulation program for ≥ 3 months;
* attendance at any excessive formal physical exercise or sports program.

Where this trial is running

Kaunas

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Healthy
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.