Effects of hormone therapy and exercise on health in postmenopausal women
De Invloed Van Hormoonsubstitutietherapie en Gesuperviseerde Training op Lichaamssamenstelling, Cardiovasculair Risico en Insulinegevoeligheid Bij Postmenopauzale Vrouwen
This study tests if combining exercise with hormone therapy can improve health markers in postmenopausal women.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 390 (estimated) |
| Ages | 45 Years to 65 Years |
| Sex | Female |
| Sponsor | University Hospital, Ghent Academic / other |
| Locations | 1 site (Ghent) |
| Trial ID | NCT05831709 on ClinicalTrials.gov |
What this trial studies
This trial investigates the combined effects of supervised exercise training and hormone replacement therapy on various health outcomes in postmenopausal women. A total of 270 participants will engage in a structured exercise program lasting between 12 to 24 weeks. The study aims to assess changes in body composition, cardiovascular risk, insulin sensitivity, and other health markers. By focusing on this specific demographic, the trial seeks to provide insights into effective interventions for improving health in postmenopausal women.
Who should consider this trial
Good fit: Ideal candidates for this study are postmenopausal women in good general health with a BMI between 20 and 30 kg/m2.
Not a fit: Patients who are not yet in menopause or have a BMI outside the range of 20-30 kg/m2 may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes and quality of life for postmenopausal women.
How similar studies have performed: Other studies have shown promising results with similar approaches combining exercise and hormone therapy in improving health outcomes for postmenopausal women.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Postmenopausal women (diagnosed by physician) with complaints due to menopause * Indication for hormonal substitution therapy (except for the control group) * Good general health * BMI: 20-30 kg/m2 * Only the use of cholesterol-, blood pressure- or/and thyroid-regulating medication is permitted
Where this trial is running
Ghent
- Ghent University Hospital - Women's Clinic — Ghent, Belgium (Recruiting)
Study contacts
- Study coordinator: Herman Depypere
- Email: studieco.vrouwenkliniek@uzgent.be
- Phone: 003293323783
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.