Effects of higher dietary protein on sleep quality in older adults in Singapore
Impact of Different Types of Higher Dietary Protein Intake on Sleep Quality in Singapore Older Adults
This study is testing if eating more protein from different sources can improve sleep quality for older adults in Singapore.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 54 (estimated) |
| Ages | 60 Years to 85 Years |
| Sex | All |
| Sponsor | National University of Singapore Academic / other |
| Locations | 1 site (Singapore) |
| Trial ID | NCT05400005 on ClinicalTrials.gov |
What this trial studies
This study investigates how different types of higher dietary protein intake affect sleep quality among older adults aged 60-85 in Singapore. Participants will be randomly assigned to one of three groups: a normal-protein diet, a higher-protein diet supplemented with micellar casein protein, or a higher-protein diet supplemented with soy protein. The intervention will last for 16 weeks, during which dietary compliance will be monitored through regular contact and assessments. The study aims to clarify the impact of dietary protein sources on sleep quality, particularly in the context of increased psychological distress due to the COVID-19 pandemic.
Who should consider this trial
Good fit: Ideal candidates are older adults aged 60-85 who are not currently following a healthy eating pattern diet.
Not a fit: Patients who have experienced significant weight changes, engage in vigorous exercise, or have certain medical conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to dietary recommendations that improve sleep quality and overall health in older adults.
How similar studies have performed: While the effects of dietary protein on sleep quality have been explored, this specific approach comparing animal-sourced and plant-sourced protein in older adults is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Adults 60-85 years old 2. Not following HPB diet Exclusion Criteria: 1. Weight change \> 3kg in the past 3 months 2. Exercise vigorously over the past 3 months 3. Drinking more than 2 alcoholic drinks per day 4. (if applicable) Pre-menopausal women 5. Taking dietary supplements or medications which may impact sleep outcomes (e.g. Nutritional Shakes (e.g. Ensure), Trp, 5-HTP or melatonin supplementations) the past 1 month 6. Taking dietary supplements which may impact the gut microbiota (e.g. antibiotics, prebiotics, probiotics) the past 2 months (a list of fermented foods) 7. Impaired renal function (normal values: estimated glomerular filtration rate ≥ 90 mL/min/1.73 m2 calculated by chronic kidney disease epidemiology collaboration equation; CKD EPI) 8. Soy intolerance and/or allergy or any medical conditions that may be affected by consumption of soy products (e.g. gout) 9. Prescribed and taking antihypertensive/cholesterol-lowering/ type-2 diabetic medication or Chinese medicine herb which started less than 3 years prior to the intervention participation 10. Diagnosed with gut/gastrointestinal issues such as lactose intolerance and irritable bowel syndrome (IBS)
Where this trial is running
Singapore
- National University of Singapore — Singapore, Singapore (Recruiting)
Study contacts
- Principal investigator: Jung Eun Kim, PhD — National University of Singapore
- Study coordinator: Clarinda N Sutanto, PhD
- Email: cnsfst@nus.edu.sg
- Phone: 83787674
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.