Effects of High-Intensity Interval Training on Obesity and Metabolic Health
The Effect of High-Intensity Interval Training on Cardiometabolic Risk Factors, Body Composition, and Plasma FABP4 Levels in Sedentary Obese Adults.
This study tests if high-intensity interval training can help sedentary obese adults improve their health and body composition by looking at changes in certain risk factors and a specific protein.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 28 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | All |
| Sponsor | Eastern Mediterranean University Academic / other |
| Locations | 1 site (Famagusta) |
| Trial ID | NCT06973980 on ClinicalTrials.gov |
What this trial studies
This study investigates how high-intensity interval training (HIIT) affects metabolic risk factors, body composition, and levels of Fatty Acid Binding Protein 4 (FABP4) in sedentary obese adults. Participants aged 20 to 35 with a BMI between 30 and 35 kg/m² will engage in a structured exercise program. The study aims to determine whether HIIT can improve health markers associated with obesity and metabolic diseases, particularly focusing on the role of FABP4 as a biomarker. The research will assess changes in cardiometabolic risk factors and body composition before and after the intervention.
Who should consider this trial
Good fit: Ideal candidates are sedentary obese adults aged 20 to 35 with a BMI between 30 and 35 kg/m².
Not a fit: Patients with a BMI over 35, serious cardiovascular or respiratory diseases, neurological disorders, or significant musculoskeletal issues may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide a new exercise-based approach to reduce obesity-related health risks and improve metabolic health in sedentary individuals.
How similar studies have performed: Previous studies have shown promising results for HIIT in improving metabolic health, suggesting this approach may be effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 20 and 35 years, * BMI between 30 and 35 kg/m², * Waist circumference of 90-100 cm for women, 105-110 cm for men, * Sedentary lifestyle (\<600 MET-min/week), * Referred by a physician (with a statement confirming no contraindication to exercise)." Exclusion Criteria: * BMI \> 35, * Pregnancy, * Cardiovascular Diseases: Individuals with serious cardiovascular issues, such as uncontrolled hypertension, heart failure, coronary artery disease, or a heart attack within the last 6 months, which could pose a risk during exercise. * Respiratory Diseases: Individuals with chronic respiratory conditions, such as uncontrolled or severe asthma or COPD, who cannot tolerate exercise due to their condition. * Neurological Disorders: Individuals with neurological issues that limit exercise capacity, such as Parkinson's disease, stroke, or multiple sclerosis. * Musculoskeletal Issues: Individuals with chronic musculoskeletal problems, particularly knee or hip osteoarthritis, that may increase the risk of pain or injury during exercise. * Metabolic or Endocrine Disorders: Individuals with uncontrolled metabolic issues, such as diabetes or thyroid disorders, that could cause blood sugar or hormonal fluctuations during exercise. * Acute Infections or Illness: Individuals with acute infections, fever, or recently undergone surgical procedures. * Any health condition that may prevent participation in exercise."
Where this trial is running
Famagusta
- Eastern Mediterranean University — Famagusta, Cyprus (Recruiting)
Study contacts
- Principal investigator: YAŞAM DİREL, MSc — Eastern Meditterean university
- Study coordinator: YAŞAM DİREL, MSc
- Email: yasamdirel001@gmail.com
- Phone: 0090 392 6303939
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.