Effects of green light exposure on pain in hypermobile Ehlers-Danlos Syndrome

Investigation of Light Exposure on Pain Severity and Quality of Life in Individuals With Hypermobile Ehlers-Danlos Syndrome: A Pilot Study

Not applicable Interventional New York Institute of Technology · NCT05561270

This study is testing whether exposure to green light can help reduce pain for people with hypermobile Ehlers-Danlos Syndrome.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorNew York Institute of Technology Academic / other
Locations1 site (Old Westbury, New York)
Trial IDNCT05561270 on ClinicalTrials.gov

What this trial studies

This investigation focuses on the impact of green light exposure on pain severity and symptoms in individuals diagnosed with hypermobile Ehlers-Danlos Syndrome (hEDS). Chronic pain is a significant issue for these patients, often affecting their quality of life. The study will utilize both white and green LED light to assess changes in pain levels reported by participants. By exploring this non-pharmacological approach, the research aims to provide insights that could enhance treatment strategies for hEDS patients.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with hEDS and experience significant chronic pain.

Not a fit: Patients who have recently started new analgesic therapy or have serious mental health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could offer a new non-pharmacological treatment option for managing chronic pain in hEDS patients.

How similar studies have performed: Previous studies have shown promise in using colored light therapies for pain management, indicating potential for success in this novel approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. 18 years of age or older and able to speak, read, and understand English
2. Diagnosed with hEDS
3. Average numeric pain score of 5 out of 10 or greater over the 10 weeks prior to enrolling in the study and failure of medical therapy to control the pain

Exclusion Criteria:

1. Initiation of any new analgesic therapy within 30 days of enrollment (note: chronic therapy with a stable regimen maintained for at least 30 days prior to enrollment is permitted)
2. Serious mental illness, defined as distortions of perception, delusions, hallucinations, and unusual behaviors resulting in loss of contact with reality or Major Depression Disorder
3. History of color blindness or uncorrected cataracts
4. Receiving remuneration, or litigation pending, for their medical conditions

Where this trial is running

Old Westbury, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Ehlers-Danlos SyndromePain, Chronic
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.