Effects of fructose on metabolism in healthy adults
The Metabolic Response to Fructose Ingestion
NA · Baylor College of Medicine · NCT06671756
This study tests how eating fructose compares to glucose in affecting metabolism in healthy adults aged 18 to 64.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 64 Years |
| Sex | All |
| Sponsor | Baylor College of Medicine (other) |
| Locations | 1 site (Houston, Texas) |
| Trial ID | NCT06671756 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how fructose ingestion affects metabolic factors in healthy adults aged 18-64 with a BMI between 19 and 30 kg/m². Participants will consume either fructose or glucose after fasting for 8 hours, and their blood will be drawn at regular intervals to measure circulating metabolic markers, including the soluble leptin receptor. The study aims to compare the metabolic effects of fructose versus glucose consumption.
Who should consider this trial
Good fit: Ideal candidates are healthy adults aged 18-64 with a BMI between 19 and 30 kg/m².
Not a fit: Patients with significant medical conditions, fructose intolerance, or those taking medications (except oral contraceptives) may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into how fructose affects metabolism, potentially guiding dietary recommendations.
How similar studies have performed: While studies on fructose and metabolism exist, this specific comparison of fructose and glucose in healthy adults is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age: Participants must be between 18 and 64 years old. * BMI: Participants must have a Body Mass Index (BMI) between 19 and 30 kg/m² (healthy weight to slightly overweight). * Health Status: Participants must be healthy volunteers with no significant medical conditions. * Sex/Gender: Both males and females are eligible to participate. Exclusion Criteria: * Known significant medical illness, any medications except oral contraceptives, history of fructose intolerance, pregnancy. We will not enroll BCM Medical students or individuals who work directly for any of the study investigators.
Where this trial is running
Houston, Texas
- Baylor St. Luke's Medical Center — Houston, Texas, United States (RECRUITING)
Study contacts
- Study coordinator: Lu Xu, MD, PhD
- Email: lu.xu@bcm.edu
- Phone: 713-798-1707
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Healthy, Fructose, Metabolism, Soluble Leptin Receptor