Effects of fluid infusion rates on blood circulation during surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the impact of intraoperative fluid therapy on microcirculation during elective surgeries with minimal blood loss. It aims to optimize fluid infusion rates to enhance oxygen supply to tissues while minimizing hemodilution caused by endothelial glycocalyx damage. The research will analyze flow parameters in microcirculation based on different fluid infusion rates, providing insights into the optimal management of fluid therapy in surgical settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* elective recumbent and laparoscopic surgery
* informed consent

Exclusion Criteria:

* blood loss over 250 ml
* hemodynamic instability requiring noradrenaline infusion

Where it's running

• University Hospital Hradec Kralove
  Hradec Králové, Czechia Recruiting

Study contacts

• Study coordinator: David Astapenko, MD, PhD
• Email: david.astapenko@fnhk.cz
• Phone: +420495833218

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.