Effects of Feeding Position on Preterm Infants' Health

The Effect of Position Given to Preterms After Feeding on Gastric Residual Volume, Abdominal Oxygenation and Fractional Oxygen Extraction

NA · Istanbul University - Cerrahpasa · NCT05888090

This study tests how different feeding positions can affect the health of stable preterm babies to see which position might be best for them.

Quick facts

PhaseNA
Study typeInterventional
Enrollment48 (estimated)
Ages28 Weeks to 33 Weeks
SexAll
SponsorIstanbul University - Cerrahpasa (other)
Locations1 site (Merkez, Isparta)
Trial IDNCT05888090 on ClinicalTrials.gov

What this trial studies

This study investigates how different positions after feeding affect gastric residual volume, abdominal oxygenation, and fractional oxygen extraction in clinically stable preterm newborns. Using a randomized crossover design, 48 participants will be assigned to three intervention groups, each experiencing three positions: prone, right lateral, and semi-elevated supine. Each position will be applied once to each participant, and their responses will be monitored for two hours post-feeding. The study aims to provide insights into optimal positioning for improving health outcomes in preterm infants.

Who should consider this trial

Good fit: Ideal candidates are clinically stable preterm newborns aged 28-33 weeks of gestation who are breastfed and receiving enteral nutrition.

Not a fit: Patients requiring mechanical ventilation or diagnosed with gastrointestinal issues such as NEC or congenital anomalies may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance the care and health outcomes of preterm infants by identifying the best feeding positions.

How similar studies have performed: While similar studies on positioning in preterm infants exist, this specific approach and its outcomes are novel and not extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Preterm newborns who are at 28-33 weeks of gestation according to the last menstrual period of the mother,
* Preterm newborns who are breastfed,
* Preterm newborns who are clinically stable and enteral feeding started,
* Preterm newborns who are first enteral nutrition 24 hours after mechanical ventilation,
* Preterm newborns who are at least 50% of their nutrition provided with enteral nutrition,
* Free Newborns fed by flow and orogastric tube and with informed consent of the parents will be included in the study.

Exclusion Criteria:

* Preterm newborns requiring mechanical ventilation,
* Preterm newborns diagnosed with NEC,
* Preterm newborns vomiting,
* Preterm newborns who have abdominal distension,
* Preterm newborns who have nasal mechanical obstruction,
* Preterm newborns who have congenital anomalies,
* Preterm newborns who have gastrointestinal problems such as gastroschisis or congenital diaphragmatic hernia,
* Preterm newborn who have cerebrovascular disease, apnea episodes, severe neurological disease, were included in the study. will not be included,
* Preterm newborns who worsen clinically after inclusion in the sample group will be excluded from the study.

Where this trial is running

Merkez, Isparta

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Gastric Residual Volume, Abdominal Oxygenation, Fractional Oxygen Extraction, Positioning, Preterm Infants

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.