Effects of exercise programs on fatigue in patients with persistent COVID

Efficacy of Two Therapeutic Exercise Modalities for Patients With Persistent COVID: Pilot Study

Not applicable Interventional Facultat de ciencies de la Salut Universitat Ramon Llull · NCT06142240

This study tests whether two different exercise programs can help people with ongoing fatigue from COVID-19 feel better after 8 weeks of training.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment40 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorFacultat de ciencies de la Salut Universitat Ramon Llull Academic / other
Locations1 site (Barcelona, Vilafranca Del Penedés)
Trial IDNCT06142240 on ClinicalTrials.gov

What this trial studies

This study evaluates the impact of two different therapeutic exercise modalities on fatigue perception in patients suffering from persistent COVID-19. Participants will be randomly assigned to either a supervised exercise program at a health center or a home-based program with telematic supervision. Both groups will engage in an 8-week exercise regimen consisting of muscle strength training and aerobic training. The primary focus is to assess changes in fatigue levels resulting from these interventions.

Who should consider this trial

Good fit: Ideal candidates include adult patients diagnosed with Long COVID-19 who are willing to participate in the exercise program.

Not a fit: Patients with significant comorbidities or those who regularly engage in intense sports may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide effective exercise strategies to alleviate fatigue in patients with persistent COVID-19.

How similar studies have performed: While there is limited research specifically on exercise modalities for persistent COVID, similar approaches in managing fatigue in other chronic conditions have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients diagnosed with LongCOVID19 or persistent COVID19.
* Agree to participate and sign the informed consent form.

Exclusion Criteria:

* Patients with comorbidities associated with having fatigue (e.g. cancer survivors, severe cardiovascular or respiratory disease prior to persistent COVID).
* Taking medication of drugs that may interfere with the perception of fatigue.
* Patients with mental disorders or cognitive impairment prior to persistent COVID.
* Patients who regularly practice intense sports (\>4h/week).
* Any illness that may condition understanding and compliance with the study.

Where this trial is running

Barcelona, Vilafranca Del Penedés

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Persistent COVID-19
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.