Effects of exercise on schizophrenia symptoms and quality of life for patients on clozapine

Investigating the Effect of Exercise on Clinical Symptoms, Cognitive Performance, and Quality of Life in Schizophrenia Patients Treated With Clozapine

NA · Dr. Lutfi Kirdar Kartal Training and Research Hospital · NCT06573320

This study tests if regular exercise can improve symptoms and quality of life for people with schizophrenia who are taking clozapine.

Quick facts

PhaseNA
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorDr. Lutfi Kirdar Kartal Training and Research Hospital (other gov)
Locations1 site (Istanbul)
Trial IDNCT06573320 on ClinicalTrials.gov

What this trial studies

This study investigates how physical exercise impacts clinical symptoms, cognitive performance, and overall quality of life in patients with schizophrenia who are being treated with clozapine. The research focuses on individuals diagnosed with schizophrenia according to DSM-V criteria and receiving a therapeutic dose of clozapine. By assessing the effects of exercise, the study aims to provide insights into potential non-pharmacological interventions that could enhance treatment outcomes for these patients.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with schizophrenia who are currently being treated with a therapeutic dose of clozapine.

Not a fit: Patients who are pregnant will not benefit from this study due to exclusion criteria.

Why it matters

Potential benefit: If successful, this study could improve the management of schizophrenia symptoms and enhance the quality of life for patients on clozapine.

How similar studies have performed: While the approach of combining exercise with pharmacological treatment in schizophrenia is gaining interest, this specific study's focus on clozapine is relatively novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients treated who were diagnosed with schizophrenia according to DSM-V criteria by psychiatrist at the Turkish Ministry of Health Kartal Dr. Lütfi Kırdar City Hospital
* using a therapeutic dose of 300-500 mg/day of clozapine,

Exclusion Criteria:

* pregnancy

Where this trial is running

Istanbul

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Schizophrenia, Clozapine, Exercise

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.