Effects of exercise on prediabetic individuals

Comparison of the Effects of High-Intensity Interval Exercise Training and Moderate-Intensity Continuous Exercise Training in Prediabetic Individuals: Single-Blind Randomized Controlled Study

Not applicable Interventional Eastern Mediterranean University · NCT06831266

This study is testing whether High Intensity Interval Training or Moderate Intensity Continuous Training is better at improving health for people at risk of diabetes.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment24 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorEastern Mediterranean University Academic / other
Locations2 sites (Mersin, Kyrenia and 1 other locations)
Trial IDNCT06831266 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the impact of two different exercise protocols, High Intensity Interval Training (HIIT) and Moderate Intensity Continuous Training (MICT), on various health metrics in individuals at risk for diabetes. Participants will be randomly assigned to one of the two exercise groups after providing informed consent. The study will assess changes in body composition, aerobic capacity, blood lipid profiles, biomarkers, quality of life, and exercise beliefs. The goal is to determine which exercise regimen is more effective in improving health outcomes for prediabetic individuals.

Who should consider this trial

Good fit: Ideal candidates for this study are sedentary individuals aged 18-60 with a HbA1c value between 5.7%-6.4% and a BMI greater than 24.9 kg/m².

Not a fit: Patients who are on insulin or derivative drugs, have uncontrolled hypertension, or have a history of heart disease, myocardial infarction, or stroke may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide insights into effective exercise strategies for preventing the progression of prediabetes to type 2 diabetes.

How similar studies have performed: Other studies have shown positive outcomes with exercise interventions in prediabetic populations, suggesting that this approach is promising.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Being between 18-60 years old
* HbA1c value between 5.7%-6.4%
* BMI\>24,9 kg/m²
* Being sedentary
* Not on any diet

Exclusion Criteria:

* Insulin and derivative drug use
* Uncontrolled hypertension
* History of heart disease
* History of MI or stroke

Where this trial is running

Mersin, Kyrenia and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Prediabetes / Type 2 Diabetesexerciseanti-inflammatory markersaerobic capacity
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.