Effects of exercise on patients undergoing haemodialysis
Effect of Active Exercise on Nutritional and Inflammatory Status, Muscle Metabolism and Cardiovascular Events in Maintenance Haemodialysis Patients
This study is testing if low-intensity exercise, like walking or Tai Chi, can help people on dialysis feel better and reduce health problems related to nutrition and inflammation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 75 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital of Chongqing Medical University Academic / other |
| Locations | 1 site (Chongqing, Chongqing Municipality) |
| Trial ID | NCT06568835 on ClinicalTrials.gov |
What this trial studies
This clinical trial investigates how physical activity influences nutrition, inflammation, muscle metabolism, and the risk of cardiovascular and cerebrovascular events in patients receiving maintenance haemodialysis. Participants will engage in low-intensity aerobic exercises, such as walking or Tai Chi, for at least 30 minutes, three times a week, while their progress will be compared to a conventional treatment group. The study aims to determine if exercise can enhance nutritional and inflammatory status, improve muscle strength, and reduce health complications in these patients.
Who should consider this trial
Good fit: Ideal candidates are patients who have been on maintenance haemodialysis for more than three months and are in stable condition without serious infections or cardiovascular diseases.
Not a fit: Patients with severe heart or lung diseases, or those with chronic joint, muscle, or vascular conditions that prevent regular exercise, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved health outcomes and quality of life for patients on maintenance haemodialysis through the incorporation of exercise into their treatment regimen.
How similar studies have performed: Other studies have shown promising results regarding the benefits of exercise for patients undergoing dialysis, suggesting that this approach is both relevant and potentially effective.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * MHD more than 3 months, 3 times per week, 3-4h each time; * Urea clearance index (Kt/V) \>1.2; * Stable condition, no serious infection, tumour and cardiovascular disease; * Willing to join the study and sign the informed consent form. Exclusion Criteria: * Combined with serious heart and lung disease: such as repeated heart failure, severe arrhythmia, unstable angina pectoris, severe pericardial effusion, severe heart valve disease, hypertrophic cardiomyopathy, aortic coarctation, severe emphysema, pulmonary heart disease, severe pulmonary hypertension (average pressure of the pulmonary artery \> 55mmHg), etc.; * Combined with chronic joints, muscles, or vascular disease can not be or is not suitable for regular exercise, such as cerebrovascular disease; combined chronic joint, muscle or vascular disease can not or are not suitable for regular exercise, such as cerebrovascular disease sequelae, serious lower limb joint damage, severe myopathy, deep vein thrombosis, etc.; * unwilling to cooperate with the movement of people
Where this trial is running
Chongqing, Chongqing Municipality
- The First Affiliated Hospital of Chongqing Medical University — Chongqing, Chongqing Municipality, China (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.