Effects of Exercise on Pain and Recovery After Concussion in College Athletes

The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes: A Randomized Controlled Trial

Not applicable Interventional University of Virginia · NCT06246669

This study is testing if different levels of aerobic exercise can help college athletes recover from concussions faster and feel better emotionally.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment46 (estimated)
Ages18 Years to 25 Years
SexAll
SponsorUniversity of Virginia Academic / other
Locations1 site (Charlottesville, Virginia)
Trial IDNCT06246669 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates how prescribed aerobic exercise at different intensities affects psychological measures and recovery time in collegiate athletes diagnosed with a concussion. Participants will be randomly assigned to either a light or moderate intensity treadmill walking group, starting their exercise protocol 48 hours post-diagnosis. The study aims to determine if the intensity of exercise influences pain-related fear, anxiety, depression, and overall symptom recovery. The exercise sessions will occur five times a week until participants report being symptom-free.

Who should consider this trial

Good fit: Ideal candidates are collegiate athletes who are symptomatic following a concussion diagnosis.

Not a fit: Patients with structural brain abnormalities or other injuries preventing them from exercising will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could provide a new approach to managing concussion recovery through tailored exercise regimens.

How similar studies have performed: Previous studies have shown that exercise can positively influence recovery from concussions, making this approach promising yet still requiring further investigation.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Collegiate athlete (varsity)
* Symptomatic at time of exercise prescription

Exclusion Criteria:

* If advanced neuroimaging was performed, any subject with a structural abnormality will be excluded
* History of traumatic brain injury requiring hospitalization
* Not cleared to play their sport by a physician due to some other injury such as an ankle sprain or muscle strain
* If individual is diagnosed with any condition that is a contraindication to aerobic exercise. Please note that all participants will have already been cleared to participate in their respective collegiate sport after extensive pre-participation physical examinations upon entering the university.

Where this trial is running

Charlottesville, Virginia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Concussion, Brainkinesiophobiaexerciseanxiety
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.