Effects of exercise on muscle health in older adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project investigates how exercise impacts skeletal muscle and adipose tissue in older adults, focusing on the aging process. It employs a randomized controlled trial design with a 6-month multidomain intervention program for community-dwelling individuals aged 65 and older who exhibit early physical impairments. The study also examines blood samples to identify circulating biomarkers associated with muscle health and aging. By understanding the systemic effects of exercise, the research aims to develop strategies to counteract age-related functional decline.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* aged ≥ 65 years
* slow gait speed (\<1 m/s in 6-meter walk test) or weakness (dominant handgrip strength \<28 kg in men, \<18 kg in women)

Exclusion Criteria:

* established diagnosis of dementia, Parkinsonism or other mobility-limiting, disable conditions
* active, acute diseases receiving treatment, such as cancer, heart failure, COPD and so on
* estimated life expectancy \<12 months
* current nursing home residents

Where it's running

• Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University
  Taipei, Taiwan Recruiting

Study contacts

• Principal investigator: Li-Ning Peng, M.D., PhD — Center for Healthy Longevity and Aging Sciences, National Yang Ming Chiao Tung University
• Study coordinator: Li-Ning Peng, M.D., PhD
• Email: lining.peng@gmail.com
• Phone: +886-28239014

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.